Evidence map›Paper›PMID 34903213›Full record

ArticlePediatric rheumatology online journal2021

Cannabidiol (CBD) Use among children with juvenile idiopathic arthritis.

Christopher J Failing, Kevin F Boehnke, Meredith Riebschleger

Open access · goldAbstract read
In one paragraph

Article in Pediatric rheumatology online journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Current State of Unapproved Cannabidiol Product Use in Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christopher J Failing *Department of Pediatric Rheumatology, C.S. Mott Children's Hospital, Ann Arbor, United States, MI. chris.failing@gmail.com.
Kevin F Boehnke *University of Michigan, Ann Arbor, United States, MI.
Meredith RiebschlegerDepartment of Pediatric Rheumatology, C.S. Mott Children's Hospital, Ann Arbor, United States, MI. mriebsch@med.umich.edu.
C. S. Mott Children's Hospital · USMichigan Medicine · US

Funding

Cannabinoid Effects on Sleep and Pain Mechanisms in Osteoarthritis of the KneeK01DA049219 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, KEVIN FOXMAN · 2020 to 2023
$569k
NIDA NIH HHS K01 DA049219
6 · The paper itself

Abstract

backgroundJuvenile idiopathic arthritis (JIA) is common and difficult to treat. Cannabidiol (CBD) is now widely available, but no studies to date have investigated the use of CBD for JIA.

methodsWe performed a chart review to identify patients with JIA at a Midwestern medical institution between 2017 and 2019. We surveyed primary caregivers of JIA patients using an anonymous, online survey with questions on caregiver knowledge and attitudes towards CBD. We compared respondents with no interest in CBD use vs. those contemplating or currently using CBD using descriptive statistics.

resultsOf 900 reviewed charts, 422 met inclusion criteria. Of these, 236 consented to be sent a survey link, and n=136 (58%) completed surveys. Overall, 34.5% (n=47) of respondents reported no interest in using a CBD product for their child's JIA, while 54% (n=79) reported contemplating using CBD and 7% (n=10) reported currently giving their child CBD. Only 2% of respondents contemplating or actively using a CBD product learned about CBD from their child's rheumatologist, compared with television (70%) or a friend (50%). Most respondents had not talked to their child's rheumatologist about using CBD. Of those currently using CBD, most used oral or topical products, and only 10% of respondents (n=1) knew what dose they were giving their child.

conclusionsOur results show infrequent use but a large interest in CBD among caregivers of children with JIA. Given CBD's unknown safety profile in children with JIA, this study highlights a need for better studies and education around CBD for pediatric rheumatologists.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentArthritis, JuvenileCannabidiolChildFemaleHumansMaleParentsSurveys and QuestionnairesCannabidiolCannabidiolComplementary and integrative medicineJuvenile idiopathic arthritisPediatric rheumatology

Identifiers

PMID34903213
PMCPMC8670290
OpenAlexW4200614790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.