ArticleBMC public health2021
Facilitators and barriers to antiretroviral therapy adherence among HIV-positive adolescents living in Tanzania.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Effectiveness of health education in improving treatment adherence among patients with chronic communicable diseases: A systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2025Pooled it
- Impact of HIV-Related Stigma on Antiretroviral Therapy Adherence, Engagement and Retention in HIV Care, and Transition to Adult HIV Care in Pediatric and Young Adult Populations Living With HIV: A Literature Review.AIDS and behavior · 2025Pooled it
- The Effect of Real-Time Medication Monitoring-Based Digital Adherence Tools on Adherence to Antiretroviral Therapy and Viral Suppression in People Living With HIV: A Systematic Literature Review and Meta-Analysis.Journal of acquired immune deficiency syndromes (1999) · 2024Pooled it
- Pooled it
- Pooled it
- A Remote Intervention Based on mHealth and Community Health Workers for Antiretroviral Therapy Adherence in People With HIV: Pilot Randomized Controlled Trial.JMIR formative research · 2025Trial
- Digitally Adapting LGBTQ-Affirmative Cognitive Behavioral Therapy for Chinese Men Who Have Sex With Men Living With HIV: User-Centered Design Approach.Journal of medical Internet research · 2026Article
- HIV drug resistance and treatment success in the Republic of Congo: Implications for optimized treatment.HIV medicine · 2026Article
- Barriers and Facilitators of Access and Adherence to Antiretroviral Therapy Among Young People Living with HIV in Shinyanga Region, Tanzania.AIDS and behavior · 2026Article
- Mobile Phone Access, Usage Patterns, and Perceptions of Adolescents Living With HIV on the Use of Gamified Interventions to Improve Antiretroviral Therapy Adherence in Eswatini: Qualitative Study.JMIR mHealth and uHealth · 2026Article
- Factors associated with antiretroviral therapy adherence among adolescents living with HIV in Addis Ababa, Ethiopia: structural equation modeling.AIDS research and therapy · 2026Article
- Perceptions of adolescents and young adults failing antiretroviral therapy on adherence in Gauteng, South Africa.Southern African journal of HIV medicine · 2026Article
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- Article
- A qualitative exploration of psychosocial determinants influencing viral load suppression among adolescents living with HIV: Application of social action theory.Health SA = SA Gesondheid · 2026Article
- Challenges and Enablers of Antiretroviral Therapy Adherence Among Ethiopian Adolescents: A Qualitative Study.International journal of sexual health : official journal of the World Association for Sexual Health · 2026Article
- Experiences and perceptions on antiretroviral therapy adherence and non-adherence: a scoping review of young people living with HIV in sub-Saharan Africa.BMC public health · 2025Article
- Technology-Assisted Interventions in the Delivery of HIV Prevention, Care, and Treatment Services in Sub-Saharan Africa: Scoping Review.Journal of medical Internet research · 2025Article
- Bridging the gap: identifying barriers and strategies for widespread implementation of long-acting injectable antiretroviral therapy in Sub-Saharan Africa: a scoping review.BMC infectious diseases · 2025Article
- An updated overview on long-acting therapeutics for the prevention and treatment of human immunodeficiency virus (HIV) from a perspective of pharmaceutics.International journal of pharmaceutics · 2025Review
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAdolescents living with HIV face substandard outcomes along the continuum of care, including higher rates of poor adherence and virologic failure. Support groups have been identified as a method to improve adherence, but there is insufficient evidence regarding their effectiveness. This study seeks to examine the protective influences for and barriers to antiretroviral therapy (ART) adherence in HIV-positive adolescents living in Tanzania.
methodsThis is a qualitative study conducted in Tanzania from January to March 2018. The sample of adolescents aged 10-19 (n = 33) was purposefully selected based on age, gender, and support group attendance to capture a broad range of experiences. Participants completed an in-depth interview, covering topics such as retention in HIV services, support group experiences, and joys and challenges of adolescent life. Interviews were coded and themes related to ART adherence were identified and summarized.
resultsSupport groups helped promote adherence by improving adolescents' knowledge and confidence. Participants associated joining support groups with an improvement in health. Almost every participant described the significant positive influence a treatment supporter had on adherence. Adolescents' daily schedules and emotional state served as a barrier to adherence. Furthermore, adherence was negatively impacted by participants' fear of accidental disclosure.
conclusionLogistical and psychosocial factors can hinder adherence. Interventions that provide both education and psychosocial support, such as peer support groups, have the potential to improve health outcomes for this population, but may not address more persistent barriers to adherence rooted in lack of treatment support from family members or friends who have not been disclosed to, or lack of transportation funds/food security.
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