Evidence map›Paper›PMID 34903186›Full record

ArticleBMC pregnancy and childbirth2021

Maternal depression trajectories and child BMI in a multi-ethnic sample: a latent growth modeling analysis.

Charlotte V Farewell, Ryley Donohoe, Zaneta Thayer, James Paulson, Jacinda Nicklas, Caroline Walker, Karen Waldie, Jenn A Leiferman

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Associations of maternal alcohol and non-prescribed substance use with early child growth.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  3. Article
  4. Placental accelerated aging in antenatal depression.American journal of obstetrics & gynecology MFM · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Charlotte V FarewellDepartment of Community and Behavioral Health, Colorado School of Public Health, University of Colorado - Anschutz Medical Campus, 13001 East 17th place Mail Stop B119, Aurora, CO, 80045, USA. Charlotte.farewell@cuanschutz.edu.
Ryley DonohoeDepartment of Community and Behavioral Health, Colorado School of Public Health, University of Colorado - Anschutz Medical Campus, 13001 East 17th place Mail Stop B119, Aurora, CO, 80045, USA.
Zaneta ThayerDartmouth College, Hanover, NH, USA.
James PaulsonOld Dominion University, Norfolk University, Norfolk, VA, USA.
Jacinda NicklasDepartment of Community and Behavioral Health, Colorado School of Public Health, University of Colorado - Anschutz Medical Campus, 13001 East 17th place Mail Stop B119, Aurora, CO, 80045, USA.
Caroline WalkerUniversity of Auckland, Auckland, New Zealand.
Karen WaldieUniversity of Auckland, Auckland, New Zealand.
Jenn A LeifermanDepartment of Community and Behavioral Health, Colorado School of Public Health, University of Colorado - Anschutz Medical Campus, 13001 East 17th place Mail Stop B119, Aurora, CO, 80045, USA.
University of Colorado Anschutz Medical Campus · USUniversity of Auckland · NZColorado School of Public Health · USDartmouth College · USOld Dominion University · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

backgroundPerinatal (antenatal and postpartum) depression impacts approximately 12% of mothers. Perinatal depression can impact everyday functioning for mothers, and the relationship with, and development of, their children. The purpose of this study was to investigate depression trajectories from the antenatal period through 54-months postpartum and associations with child body mass index at 54-months postpartum.

methodsThis study applied latent growth modeling to the Growing Up in New Zealand study, which is a longitudinal pregnancy cohort study that provides nationally representative-level data, to investigate associations between depression at three time points (antenatal, 9-months postpartum, 54-months postpartum) and child body mass index at 54-months (n=4897).

resultsThe average slope of depression for this sample is low and decreases over time. When child BMI was added to the model as an outcome variable, both antenatal depression (B=.25, p<.01), and the rate of change of depression across the perinatal and postpartum periods (B=.09, p<.01) were associated with child BMI at 54-months postpartum. After controlling for sociodemographic characteristics, antenatal depression, but not the slope of depression, remained significantly associated with child BMI (B=.05, p<.05). When controlling for maternal pre-pregnancy BMI the effect of antenatal depression on child BMI at 54-months was entirely attenuated (χ

conclusionsOur findings align with the Developmental Origins of Health and Disease theory and imply that both the physical and mental health of mothers during pregnancy may be important indicators of child growth and development outcomes. Early intervention directed towards women who have even mild depression scores during pregnancy may promote healthy child development outcomes. Additionally, given the heterogeneity of depressive symptoms over time seen in this study, multiple assessment periods across the postpartum period may be valuable to adequately address and support maternal mental health.

Indexed as

Body Mass IndexChild DevelopmentChild, PreschoolCohort StudiesDepressionDepression, PostpartumEthnicityFemaleHumansInfantLatent Class AnalysisLongitudinal StudiesMothersNew ZealandPatient Health QuestionnairePregnancyAntenatal depressionChild body mass indexLatent growth modelingPerinatal depressionPerinatal mental health

Identifiers

PMID34903186
PMCPMC8667413
OpenAlexW4226028890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.