ArticleBMC infectious diseases2021
Clinical characteristics and outcome of primary brain abscess: a retrospective analysis.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- IntracranialJournal of child neurology · 2025Pooled it
- Microbiology and clinical characteristics of brain abscess in adults from 3 tertiary hospitals in Singapore - a 11-year multicenter retrospective study.BMC infectious diseases · 2026Article
- Can 3D T1 Post-Contrast MRI in A Radiomics-Machine Learning Model Distinguish Infective from Neoplastic Ring-Enhancing Brain Lesions? An Exploratory Study.Diagnostics (Basel, Switzerland) · 2026Article
- Case Report: A pediatric case of multifocalFrontiers in pediatrics · 2026Article
- Mapping the healing brain: Longitudinal MRI volumetrics and outcomes across surgical techniques for primary brain abscesses.Brain & spine · 2026Article
- Case Report: Basal ganglia brain abscess caused byFrontiers in medicine · 2026Article
- Clinical characteristics and prognostic factors in brain abscess.Surgical neurology international · 2026Article
- Clinical Outcomes and Prognostic Factors in Cerebral Abscess: Hyperglycemia as a Predictor of the Need for Prolonged Antibiotic Therapy.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Clinical Picture and Outcomes in Patients Diagnosed with Brain Abscess.Journal of clinical medicine · 2025Article
- Influence of laboratory and radiographic parameters on the clinical presentation and outcome of surgically treated patients with primary brain abscesses.Acta neurochirurgica · 2025Article
- Clinical characteristics, complications, and outcome of brain abscess treated by stereotactic aspiration: a retrospective analysis.BMC infectious diseases · 2025Article
- Clinicodemographic and Radiological Features of Infective Ring-Enhancing Brain Lesions: A 4-Year Retrospective Study at a Tertiary Referral Center.Open forum infectious diseases · 2025Article
- Brain abscess mimicking a brain tumor only realized during surgery: A case report in a resource strained environment.Surgical neurology international · 2025Article
- Multimodal deep learning model for prediction of prognosis in central nervous system inflammation.Brain communications · 2025Article
- An unusual presentation of fungal brain abscess in immunocompetent host.Pakistan journal of medical sciences · 2024Article
- Case report on successful treatment for brain abscess in a Japanese monkey (Macaca fuscata).Laboratory animal research · 2023Article
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundPatients with primary brain abscess often present with atypical symptoms, and the outcome varies. We investigated the demographic, laboratory, and neuroimaging features of patients with brain abscess at our hospital and identified factors associated with their outcomes.
methodsWe retrospectively collected the data of patients diagnosed with primary brain abscess at our hospital between January 2011 and December 2020. Their clinical characteristics, predisposing factors, laboratory and neuroimaging findings, treatment, and outcome were analyzed.
resultsOf the 57 patients diagnosed with primary abscess, 51 (89.47%) were older than 40 years, and 42 (73.68%) were male. Only eight patients (14.04%) showed the classical triad of headache, fever, and focal neurological deficit. Fifteen patients (26.31%) had comorbidities, of which diabetes mellitus was the most common. Positive intracranial purulent material cultures were obtained in 46.15% of the patients, and gram-negative enteric bacteria were found in 33.33% of them, with Klebsiella pneumoniae being the most frequently observed. Surgical treatment, most commonly in the form of stereotactic drainage, was received by 54.39% of the patients. Good outcomes were achieved in 75.44% of the patients. Multivariate logistic regression analysis showed that patients with headaches were more likely to have a poor outcome (odds ratio 6.010, 95% confidence interval 1.114-32.407, p = 0.037).
conclusionsMale patients and those older than 40 years were more susceptible to brain abscess than female patients and those younger than 40 years, respectively. Only a few patients showed the classical triad of clinical symptoms. Diabetes mellitus was the most common comorbidity. Positive intracranial specimens' culture results were uncommon, with gram-negative enteric bacteria, especially Klebsiella pneumoniae, being the main organisms found. Most patients had a good outcome, and the presence of headache may influence the outcome.
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