ArticleBMC plant biology2021
Effects of various artificial agarwood-induction techniques on the metabolome of Aquilaria sinensis.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Agarwood in the Modern Era: Integrating Biotechnology and Pharmacology for Sustainable Use.International journal of molecular sciences · 2025Pooled it
- Endophytic fungal inoculation reshapes volatile metabolism, aroma complexity, and bioactivity of agarwood essential oil.World journal of microbiology & biotechnology · 2026Article
- Anti-Inflammatory Properties of Agarwood (Aquilaria Spp.): An Integrated Review of Phytochemistry, Molecular Mechanisms, and Therapeutic Applications.Drug design, development and therapy · 2026Review
- Biohacking agarwood: the impact of fire drills and brine on endophytes and metabolites of Aquilaria sinensis.BMC plant biology · 2025Article
- Analysis of fungal composition in different layers of Bantou agarwood-forming trunk ofChinese herbal medicines · 2025Article
- Characteristics of Growth, Photosynthesis, C/N Ratio, and Antioxidant Capacity in the Seedling Stage ofPlants (Basel, Switzerland) · 2025Article
- De novo transcriptome assembly and analysis during agarwood induction in Gyrinops versteegii Gilg. seedling.Scientific reports · 2025Article
- Characterization and Analysis of 2-(2-Phenylethyl)chromone Derivatives and Sesquiterpenoids from Agarwood of Four "Qi-Nan" Clones (Molecules (Basel, Switzerland) · 2025Article
- Endophytic Microbial Community Structure and Dynamics Influence Agarwood Formation in Aquilaria malaccensis Lam.Current microbiology · 2025Article
- Combined analysis of the endophytic fungi and volatile oil content of differentFrontiers in plant science · 2025Article
- Towards sustainable agarwood production: integrating microbial interactions, anatomical changes, and metabolite biosynthesis.Journal of industrial microbiology & biotechnology · 2024Review
- Dynamics of Physiological Properties and Endophytic Fungal Communities in the Xylem ofJournal of fungi (Basel, Switzerland) · 2024Article
- Physiological characteristics during the formation of aromatic components in xylem ofFrontiers in plant science · 2024Article
- FeedingFoods (Basel, Switzerland) · 2023Article
- Rediscovering the Therapeutic Potential of Agarwood in the Management of Chronic Inflammatory Diseases.Molecules (Basel, Switzerland) · 2022Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAgarwood is a highly sought-after resinous wood for uses in medicine, incense, and perfume production. To overcome challenges associated with agarwood production in Aquilaria sinensis, several artificial agarwood-induction treatments have been developed. However, the effects of these techniques on the metabolome of the treated wood samples are unknown. Therefore, the present study was conducted to evaluate the effects of four treatments: fire drill treatment (F), fire drill + brine treatment (FS), cold drill treatment (D) and cold drill + brine treatment (DS)) on ethanol-extracted oil content and metabolome profiles of treated wood samples from A. sinensis.
resultsThe ethanol-extracted oil content obtained from the four treatments differed significantly (F < D < DS < FS). A total of 712 metabolites composed mostly of alkaloids, amino acids and derivatives, flavonoids, lipids, phenolic acids, organic acids, nucleotides and derivatives, and terpenoids were detected. In pairwise comparisons, 302, 155, 271 and 363 differentially accumulated metabolites (DAM) were detected in F_vs_FS, D_vs_DS, F_vs_D and FS_vs_DS, respectively. The DAMs were enriched in flavonoid/flavone and flavonol biosynthesis, sesquiterpenoid and triterpenoid biosynthesis. Generally, addition of brine to either fire or cold drill treatments reduced the abundance of most of the metabolites.
conclusionThe results from this study offer valuable insights into synthetically-induced agarwood production in A. sinensis.
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