Evidence map›Paper›PMID 34903127›Full record

ArticleBioengineered2021

Long non-coding RNA titin-antisense RNA1 contributes to growth and metastasis of cholangiocarcinoma by suppressing microRNA-513a-5p to upregulate stratifin.

Yang Liu, Jiangyang Sun, Peng Qi, Yang Liu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yang LiuDepartment of Hepatobiliary Surgery, Huanggang Center Hospital, Huanggang, Hubei, China.
Jiangyang SunDepartment of Hepatobiliary Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Peng QiDepartment of General Surgery, Hubei No. 3 People's Hospital of Jianghan University, Wuhan, Hubei, China.
Yang LiuDepartment of General Surgery, Hubei No. 3 People's Hospital of Jianghan University, Wuhan, Hubei, China.
Huanggang Central Hospital · CNHuazhong University of Science and Technology · CNJianghan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) is one of the most common histological types of primary hepatic malignancy and is associated with poor overall prognosis, causing a ponderous burden on human life. Hence, it is necessary to elucidate the pathogenesis of CCA. The objective of our research was to shed light on the mechanism through which long non-coding RNA titin-antisense RNA1 (lncRNA TTN-AS1) is involved in the development of CCA. Reverse transcription quantitative polymerase chain reaction was used to detect TTN-AS1 expression in CCA samples and cells. Functional experiments were performed using the Cell Counting Kit-8, 5-ethynyl-2'-deoxyuridine, transwell, and

Indexed as

Gene Expression Regulation, Neoplastic14-3-3 ProteinsBase SequenceCell Line, TumorCell MovementCell ProliferationCholangiocarcinomaExoribonucleasesFemaleGene SilencingHumansMaleMicroRNAsMiddle AgedNeoplasm MetastasisRNA, Long Noncoding14-3-3 ProteinsExoribonucleasesMicroRNAsMIRN513A1 microRNA, humanRNA, Long NoncodingSFN protein, humanCholangiocarcinomalncRNAmiR-513a-5pSFNTTN-AS1

Identifiers

PMID34903127
PMCPMC8810091
OpenAlexW4200320001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.