Evidence map›Paper›PMID 34903103›Full record

ArticleTrends in hearing

Predictive models for cochlear implant outcomes: Performance, generalizability, and the impact of cohort size.

Elaheh Shafieibavani, Benjamin Goudey, Isabell Kiral, Peter Zhong, Antonio Jimeno-Yepes, Annalisa Swan, Manoj Gambhir, Andreas Buechner, Eugen Kludt, Robert H Eikelboom and 5 more

Open access · goldAbstract read
In one paragraph

Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

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  10. Changes in participatory and societal outcomes during the waiting period for cochlear implantation - an observational study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 4 countries.

Elaheh Shafieibavani127113IBM Research Australia, Southbank, Victoria, Australia.ORCID 0000-0001-8546-1217
Benjamin Goudey127113IBM Research Australia, Southbank, Victoria, Australia.ORCID 0000-0002-2318-985X
Isabell Kiral127113IBM Research Australia, Southbank, Victoria, Australia.
Peter Zhong127113IBM Research Australia, Southbank, Victoria, Australia.
Antonio Jimeno-Yepes127113IBM Research Australia, Southbank, Victoria, Australia.
Annalisa Swan127113IBM Research Australia, Southbank, Victoria, Australia.
Manoj Gambhir127113IBM Research Australia, Southbank, Victoria, Australia.
Andreas Buechner9177Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany.
Eugen Kludt9177Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany.ORCID 0000-0001-7030-7604
Robert H Eikelboom104182Ear Science Institute Australia, Subiaco, Western Australia, Australia.ORCID 0000-0003-2911-5381
Cathy Sucher104182Ear Science Institute Australia, Subiaco, Western Australia, Australia.
Rene H GiffordDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America.ORCID 0000-0001-6662-3436
Riaan Rottier104148Cochlear Limited, New South Wales, Australia.ORCID 0000-0001-7299-5412
Kerrie Plant104148Cochlear Limited, New South Wales, Australia.ORCID 0000-0002-9891-2803
Hamideh Anjomshoa127113IBM Research Australia, Southbank, Victoria, Australia.ORCID 0000-0002-0074-2405
IBM Research - Australia · AUCochlear (Australia) · AUMedizinische Hochschule Hannover · DEThe University of Melbourne · AUThe University of Western Australia · AUVanderbilt University Medical Center · US

Funding

Clinical Application of Spectral Envelope Perception: Cochlear Implant EvaluationR01DC013117 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GIFFORD, RENE H · 2013 to 2017
$1.6M
NIDCD NIH HHS R01 DC013117
6 · The paper itself

Abstract

While cochlear implants have helped hundreds of thousands of individuals, it remains difficult to predict the extent to which an individual's hearing will benefit from implantation. Several publications indicate that machine learning may improve predictive accuracy of cochlear implant outcomes compared to classical statistical methods. However, existing studies are limited in terms of model validation and evaluating factors like sample size on predictive performance. We conduct a thorough examination of machine learning approaches to predict word recognition scores (WRS) measured approximately 12 months after implantation in adults with post-lingual hearing loss. This is the largest retrospective study of cochlear implant outcomes to date, evaluating 2,489 cochlear implant recipients from three clinics. We demonstrate that while machine learning models significantly outperform linear models in prediction of WRS, their overall accuracy remains limited (mean absolute error: 17.9-21.8). The models are robust across clinical cohorts, with predictive error increasing by at most 16% when evaluated on a clinic excluded from the training set. We show that predictive improvement is unlikely to be improved by increasing sample size alone, with doubling of sample size estimated to only increasing performance by 3% on the combined dataset. Finally, we demonstrate how the current models could support clinical decision making, highlighting that subsets of individuals can be identified that have a 94% chance of improving WRS by at least 10% points after implantation, which is likely to be clinically meaningful. We discuss several implications of this analysis, focusing on the need to improve and standardize data collection.

Indexed as

Cochlear ImplantationCochlear ImplantsDeafnessHearing AidsSpeech PerceptionAdultHumansRetrospective StudiesTreatment Outcomecochlear implantmachine learningpredictive model

Identifiers

PMID34903103
PMCPMC8764462
OpenAlexW4200549049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.