Evidence map›Paper›PMID 34903078›Full record

ArticleAutism : the international journal of research and practice2022

Gastrointestinal concerns in children with autism spectrum disorder: A qualitative study of family experiences.

Calliope Holingue, Ohemaa Poku, Danika Pfeiffer, Sarah Murray, M Daniele Fallin

Open access · greenAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Describing the communication of autistic people during experiences of distress: A scoping review.Autism : the international journal of research and practice · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Genetic liability for gastrointestinal inflammation disorders and association with gastrointestinal symptoms in children with and without autism.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2024
    Article
  13. Review
  14. Review
  15. Prevalence of gastrointestinal symptoms among autistic individuals, with and without co-occurring intellectual disability.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  16. Review
  17. Characteristics of the autism spectrum disorder gastrointestinal and related behaviors inventory in children.Autism research : official journal of the International Society for Autism Research · 2022
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Calliope HolingueJohns Hopkins Bloomberg School of Public Health, USA.ORCID 0000-0002-8190-2385
Ohemaa PokuJohns Hopkins Bloomberg School of Public Health, USA.
Danika PfeifferKennedy Krieger Institute, USA.
Sarah MurrayJohns Hopkins Bloomberg School of Public Health, USA.
M Daniele FallinJohns Hopkins Bloomberg School of Public Health, USA.
Johns Hopkins University · USKennedy Krieger Institute · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
PSYCHIATRIC EPIDEMIOLOGY TRAINING PROGRAMT32MH014592 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HEATHER E VOLK, Peter P. Zandi · 1985 to 2026
$8.5M
Global Mental Health Training ProgramT32MH103210 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Judith Karen Bass, Sarah Sutherlin-McIvor Murray · 2015 to 2026
$4.0M
NIMH NIH HHS P30 MH043520NIMH NIH HHS T32 MH014592NIMH NIH HHS T32 MH019139NIMH NIH HHS T32 MH103210
6 · The paper itself

Abstract

lay abstractGastrointestinal problems are common in the autism spectrum disorder community and may affect both the person with autism spectrum disorder and their families. However, little research is available on the experiences of families who have a child with both autism spectrum disorder and gastrointestinal symptoms. We held one-on-one interviews with 12 parents of children who had both autism spectrum disorder and gastrointestinal symptoms. We analyzed the raw text responses from these interviews and identified four main themes. First, parents shared that their children had trouble verbally communicating when they were experiencing gastrointestinal symptoms (Theme 1). This led parents to use bodily signs, such as changes in the stool, and non-verbal behaviors, such as irritability, to recognize when their child was having gastrointestinal symptoms. Next, gastrointestinal issues affected both the child's well-being and their ability to attend class and extracurricular or social activities (Theme 2). The gastrointestinal issues also affected the family's routines, overall well-being, and their ability to go out and do activities together as a family (Theme 3). Finally, parents often had challenges receiving accessible and quality healthcare for their child's gastrointestinal problems (Theme 4). Together, these findings highlight the enormous burden that gastrointestinal symptoms have on the wellness of children with autism spectrum disorder and their families.

Indexed as

Autism Spectrum DisorderGastrointestinal DiseasesChildFamilyHumansParentsQualitative Researchautism spectrum disordermedical comorbidityqualitative research

Identifiers

PMID34903078
PMCPMC9192824
OpenAlexW4200305026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.