Evidence map›Paper›PMID 34902832›Full record

GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2021

Small Cell Lung Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.

Apar Kishor P Ganti, Billy W Loo, Michael Bassetti, Collin Blakely, Anne Chiang, Thomas A D'Amico, Christopher D'Avella, Afshin Dowlati, Robert J Downey, Martin Edelman and 24 more

2 registry-linked trialsOpen access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 353 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
353citing papers in PubMed, 4 pooled it
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05748795 unknown statusnot on this mapstarted 2023, after this paper: background citation

Microbial Colonization in Lung Cancer Patients

Typeobservational_patient_registrySponsorAssiut UniversityRan2023 to 2024Enrolled103ConditionsMicrobial ColonizationArmsbronchoscopy brochoalveolar lavage
NCT07424547 phase1recruitingnot on this mapstarted 2026, after this paper: background citation

Phase I Dose Escalation and Cohort Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

TypeinterventionalSponsorConjupro Biotherapeutics, Inc.Ran2026 to 2030Enrolled386ConditionsCancer, Solid Tumor Cancer, Advanced Metastatic Cancer, ProstateArmsSYS6043
3 · Its place in the literature

Who cites it

353 citing papers in PubMed, 4 syntheses or guidelines pooled it, 442 citations in OpenAlex.

  1. Pooled it
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  5. Trial
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  7. Evaluating the prognostic impact of multipleEuropean journal of nuclear medicine and molecular imaging · 2026
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  18. Clinical-radiopathological features and EBV DNA dynamics in nasopharyngeal neuroendocrine carcinoma: implications for prognosis and surveillance.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  19. Article
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293 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 3 countries.

Apar Kishor P GantiFred & Pamela Buffett Cancer Center.
Billy W LooStanford Cancer Institute.
Michael BassettiUniversity of Wisconsin Carbone Cancer Center.
Collin BlakelyUCSF Helen Diller Family Comprehensive Cancer Center.
Anne ChiangYale Cancer Center/Smilow Cancer Hospital.
Thomas A D'AmicoDuke Cancer Institute.
Christopher D'AvellaAbramson Cancer Center at the University of Pennsylvania.
Afshin DowlatiCase Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
Robert J DowneyMemorial Sloan Kettering Cancer Center.
Martin EdelmanFox Chase Cancer Center.
Charles FlorsheimPatient Advocate.
Kathryn A GoldUC San Diego Moores Cancer Center.
Jonathan W GoldmanUCLA Jonsson Comprehensive Cancer Center.
John C GreculaThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
Christine HannThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
Wade IamsVanderbilt-Ingram Cancer Center.
Puneeth IyengarUT Southwestern Simmons Comprehensive Cancer Center.
Karen KellyUC Davis Comprehensive Cancer Center.
Maya KhalilO'Neal Comprehensive Cancer Center at UAB.
Marianna KoczywasCity of Hope National Medical Center.
Robert E MerrittThe Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
Nisha MohindraRobert H. Lurie Comprehensive Cancer Center of Northwestern University.
Julian MolinaMayo Clinic Cancer Center.
Cesar MoranThe University of Texas MD Anderson Cancer Center.
Saraswati PokharelRoswell Park Comprehensive Cancer Center.
Sonam PuriHuntsman Cancer Institute at the University of Utah.
Angel QinUniversity of Michigan Rogel Cancer Center.
Chad RusthovenUniversity of Colorado Cancer Center.
Jacob SandsDana Farber/Brigham and Women's Cancer Center.
Rafael Santana-DavilaFred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance.
Michael ShafiqueMoffitt Cancer Center.
Saiama N WaqarSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
Kristina M GregoryNational Comprehensive Cancer Network.
Miranda HughesNational Comprehensive Cancer Network.
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · USUniversity of Colorado Denver · USBreast Cancer Research Foundation · USCancer Research Center · USCity Of Hope National Medical Center · USCleveland Clinic · USDana-Farber Brigham Cancer Center · USDuke Cancer InstituteFox Chase Cancer Center · USHuntsman Cancer Institute · USJewish Hospital · USKettering University · USMoffitt Cancer Center · USMoores Cancer CenterRobert H. Lurie Comprehensive Cancer Center of Northwestern UniversitySmilow Cancer Hospital · USSouthwestern Medical Center · USStanford Cancer InstituteSusan Thompson Buffett Foundation · USThe University of Texas MD Anderson Cancer Center · US

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung Cancer (SCLC) provide recommended management for patients with SCLC, including diagnosis, primary treatment, surveillance for relapse, and subsequent treatment. This selection for the journal focuses on metastatic (known as extensive-stage) SCLC, which is more common than limited-stage SCLC. Systemic therapy alone can palliate symptoms and prolong survival in most patients with extensive-stage disease. Smoking cessation counseling and intervention should be strongly promoted in patients with SCLC and other high-grade neuroendocrine carcinomas. The "Summary of the Guidelines Updates" section in the SCLC algorithm outlines the most recent revisions for the 2022 update, which are described in greater detail in this revised Discussion text.

Indexed as

Lung NeoplasmsSmall Cell Lung CarcinomaHumansMedical OncologyNeoplasm Recurrence, Local

Identifiers

PMID34902832
PMCPMC10203822
OpenAlexW4200477716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.