Evidence map›Paper›PMID 34902574›Full record

ArticleNeurobiology of learning and memory2022

Serotonin 1B receptor effects on response inhibition are independent of inhibitory learning.

Stephanie S Desrochers, Katherine M Nautiyal

Open access · greenAbstract read
In one paragraph

Article in Neurobiology of learning and memory, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Striatal Serotonin Release Signals Reward Value.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephanie S DesrochersDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, United States.
Katherine M NautiyalDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, United States. Electronic address: katherine.nautiyal@dartmouth.edu.
Dartmouth College · US

Funding

Serotonin modulation of the development of neural circuits underlying reward processing and impulsivity in adolescentsR01MH126178 · NIMH · DARTMOUTH COLLEGE · PI NAUTIYAL, KATHERINE M · 2021 to 2025
$2.8M
Dissecting serotonergic and dopaminergic contributions to the neural circuits underlying impulsive behavior.R00MH106731 · NIMH · DARTMOUTH COLLEGE · PI NAUTIYAL, KATHERINE M · 2018 to 2020
$840k
NIMH NIH HHS R00 MH106731NIMH NIH HHS R01 MH126178
6 · The paper itself

Abstract

Impulsivity is defined in terms of deficits in instrumental response inhibition, when the inability to withhold an action produces a negative outcome. However, there are many behavioral and cognitive constructs which theoretically could contribute to disordered impulsivity, including Pavlovian responding, which few studies have considered in this context. In the present set of studies, we examine Pavlovian inhibitory learning and excitatory responding in a mouse model for dysregulated impulsivity, specifically, mice lacking the serotonin 1B receptor (5-HT

Indexed as

Impulsive BehaviorInhibition, PsychologicalReceptor, Serotonin, 5-HT1BReinforcement, PsychologyAnimalsConditioning, ClassicalCuesFemaleMaleMiceMice, KnockoutReinforcement ScheduleReceptor, Serotonin, 5-HT1B5-HT(1B) receptorClassical conditioningConditioned inhibitionImpulsive actionInstrumental conditioningPavlovian appetitive conditioning

Identifiers

PMID34902574
PMCPMC8900532
OpenAlexW4200131682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.