Evidence map›Paper›PMID 34902571›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2023

Risk of Hepatocellular Carcinoma in Patients With Indeterminate (LI-RADS 3) Liver Observations.

Ashwini Arvind, Sagar Joshi, Timothy Zaki, Daniel Burkholder, Neehar D Parikh, Amit G Singal, North American Liver Cancer (NALC) Consortium

Abstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Financial Burden of Hepatocellular Carcinoma Screening in Patients With Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. [Expert consensus on the diagnosis, treatment, and management of liver nodules (version 2026)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Hepatocellular Carcinoma Surveillance Patterns and Outcomes in Patients With Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashwini ArvindDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Sagar JoshiDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Timothy ZakiDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Daniel BurkholderDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Neehar D ParikhDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Amit G SingalDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas; Department of Internal Medicine, Parkland Health and Hospital System, Dallas, Texas. Electronic address: amit.singal@utsouthwestern.edu.
North American Liver Cancer (NALC) Consortium

Funding

Trial of Statins for Chemoprevention in Hepatocellular CarcinomaR01CA255621 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T, HOSHIDA, YUJIN · 2021 to 2025
$3.6M
Precision Risk Stratification and Screening for HCC among Patients with Cirrhosis in the United StatesU01CA230694 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SINGAL, AMIT · 2018 to 2022
$3.5M
Reverse-engineering precision liver cancer chemopreventionR01CA233794 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HOSHIDA, YUJIN · 2019 to 2023
$3.5M
Harms of Hepatocellular Carcinoma Screening in Patients with CirrhosisR01CA212008 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SINGAL, AMIT · 2017 to 2022
$3.2M
NCI NIH HHS R01 CA212008NCI NIH HHS R01 CA233794NCI NIH HHS R01 CA255621NCI NIH HHS U01 CA230694
6 · The paper itself

Abstract

Early hepatocellular cancer (HCC) detection is associated with curative treatment and improved survival.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsContrast MediaHumansLiverLiver CirrhosisMagnetic Resonance ImagingRetrospective StudiesSensitivity and SpecificityContrast Media

Identifiers

PMID34902571
PMCPMC9184301

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.