Evidence map›Paper›PMID 34902392›Full record

ReviewCurrent problems in cardiology2022

Clinical Cardiovascular Adverse Events Reported Post-COVID-19 Vaccination: Are They a Real Risk?

David Hana, Kevin Patel, Sherif Roman, Boula Gattas, Sarah Sofka

Open access · greenAbstract readReview
In one paragraph

Review in Current problems in cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. COVID-19 and cardiovascular disease in patients with chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Review
  9. Review
  10. [Myocarditis following mRNA vaccine].Wiener medizinische Wochenschrift (1946) · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Distinct Features of Vascular Diseases in COVID-19.Journal of inflammation research · 2023
    Review
  15. Article
  16. Article
  17. Clinical cardiovascular emergencies and the cellular basis of COVID-19 vaccination: from dream to reality?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Review
  18. Article
  19. Link between COVID-19 vaccines and myocardial infarction.World journal of clinical cases · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

David HanaDepartment of Medicine, West Virginia University School of Medicine, Morgantown, WV. Electronic address: David.hana@hsc.wvu.edu.
Kevin PatelDepartment of Medicine, University of Tennessee Health Science Center, Memphis, TN.
Sherif RomanDepartment of Medicine, St Joseph's University Medical Center, Paterson, NJ.
Boula GattasDepartment of Medicine, St Mary Medical Center, Langhorne, PA.
Sarah SofkaDepartment of Medicine, West Virginia University School of Medicine, Morgantown, WV.
West Virginia University · USSt. Joseph’s University Medical Center · USSt. Mary Medical Center · USUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the urgent need to control the spread of the novel COVID-19 virus, 13 vaccines have been approved for emergency use before completing all 3 phases of the clinical trials. Thereby a careful monitor of the adverse effects postvaccination is essential. We searched through PubMed and other reporting systems like VAERS for the reported cardiovascular adverse events post-COVID-19 vaccination. Through our review, we determined that the incidence of all the reported cardiovascular events is very rare. Additionally, the vaccine was initially given to the elderly and high-risk populations in which cardiovascular events such as myocardial infarction and arrhythmias are already more prevalent, while other cardiovascular events such as myocarditis or vaccine-induced thrombotic thrombocytopenia were more common in younger populations. Moreover, a direct causal relationship, if any, between vaccination and adverse events is yet to be fully elucidated. Thus, at this time point, the benefits of vaccination far outweigh the risk.

Indexed as

COVID-19 VaccinesVaccinationAdverse Drug Reaction Reporting SystemsAgedCOVID-19HumansSARS-CoV-2COVID-19 Vaccines

Identifiers

PMID34902392
PMCPMC8662957
OpenAlexW4200045268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.