Evidence map›Paper›PMID 34902288›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2022

Predicting Persistent Developmental Stuttering Using a Cumulative Risk Approach.

Cara M Singer, Sango Otieno, Soo-Eun Chang, Robin M Jones

Open access · greenAbstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Risk Factors for the Development of Persistent Stuttering: What Every Pediatrician Should Know.International journal of environmental research and public health · 2022
    Article
  9. The Family History of Developmental Stuttering: A Scoping Review.International journal of language & communication disorders
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cara M SingerDepartment of Communication Sciences and Disorders, Grand Valley State University, Allendale, MI.ORCID 0000-0003-1520-0606
Sango OtienoDepartment of Statistics, Grand Valley State University, Allendale, MI.
Soo-Eun ChangDepartment of Psychiatry, University of Michigan, Ann Arbor.ORCID 0000-0003-4448-9525
Robin M JonesDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Google (United States) · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Sexual dimorphism of neural development underlying childhood stutteringR01DC011277 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Soo-Eun Chang · 2010 to 2026
$8.2M
STUTTERING AND DISORDERED PHONOLOGY IN YOUNG CHILDRENR01DC000523 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALDEN, TEDRA · 1991 to 2014
$4.3M
Impact of Emotion and Attention on Childhood Stuttering and its PersistenceR56DC000523 · NIDCD · VANDERBILT UNIVERSITY · PI WALDEN, TEDRA · 2009 to 2016
$588k
Psychophysiology of Childhood Stuttering: Cognitive-Emotional MechanismsR21DC016723 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JONES, ROBIN MICHAEL · 2018 to 2021
$514k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NICHD NIH HHS P50 HD103537NIDCD NIH HHS R01 DC000523NIDCD NIH HHS R01 DC011277NIDCD NIH HHS R21 DC016723NIDCD NIH HHS R56 DC000523
6 · The paper itself

Abstract

purposeThe purpose of this study was to explore how well a cumulative risk approach, based on empirically supported predictive factors, predicts whether a young child who stutters is likely to develop persistent developmental stuttering. In a cumulative risk approach, the number of predictive factors indicating a child is at risk to develop persistent stuttering is evaluated, and a greater number of indicators of risk are hypothesized to confer greater risk of persistent stuttering.

methodWe combined extant data on 3- to 5-year-old children who stutter from two longitudinal studies to identify cutoff values for continuous predictive factors (e.g., speech and language skills, age at onset, time since onset, stuttering frequency) and, in combination with binary predictors (e.g., sex, family history of stuttering), used all-subsets regression and receiver operating characteristic curves to compare the predictive validity of different combinations of 10 risk factors. The optimal combination of predictive factors and the odds of a child developing persistent stuttering based on an increasing number of factors were calculated.

resultsBased on 67 children who stutter (i.e., 44 persisting and 23 recovered) with relatively strong speech-language skills, the predictive factor model that yielded the best predictive validity was based on time since onset (≥ 19 months), speech sound skills (≤ 115 standard score), expressive language skills (≤ 106 standard score), and stuttering severity (≥ 17 Stuttering Severity Instrument total score). When the presence of at least two predictive factors was used to confer elevated risk to develop persistent stuttering, the model yielded 93% sensitivity and 65% specificity. As a child presented with a greater number of these four risk factors, the odds for persistent stuttering increased.

conclusionsFindings support the use of a cumulative risk approach and the predictive utility of assessing multiple domains when evaluating a child's risk of developing persistent stuttering. Clinical implications and future directions are discussed.

Indexed as

StutteringChild, PreschoolHumansLongitudinal StudiesPhoneticsSpeechSpeech Production Measurement

Identifiers

PMID34902288
PMCPMC9150747
OpenAlexW4200418252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.