Evidence map›Paper›PMID 34902242›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2022

Molecular Transport and Growth of Lipid Vesicles Exposed to Antimicrobial Peptides.

Josefine Eilsø Nielsen, Reidar Lund

Open access · hybridAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Josefine Eilsø NielsenDepartment of Chemistry, University of Oslo, Postboks 1033 Blindern, Oslo 0315, Norway.ORCID 0000-0001-9274-5533
Reidar LundDepartment of Chemistry, University of Oslo, Postboks 1033 Blindern, Oslo 0315, Norway.ORCID 0000-0001-8017-6396
University of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well-known that lipids constituting the cytoplasmic membrane undergo continuous reorganization to maintain the appropriate composition important for the integrity of the cell. The transport of lipids is controlled by mainly membrane proteins, but also spontaneous lipid transport between leaflets, lipid "flip-flop", occurs. These processes do not only occur spontaneously under equilibrium, but also promote structural rearrangements, morphological transitions, and growth processes. It has previously been shown that intravesicular lipid "flip-flop" and intervesicular lipid exchange under equilibrium can be deduced indirectly from contrast variation time-resolved small-angle neutron scattering (TR-SANS) where the molecules are "tagged" using hydrogen/deuterium (H/D) substitution. In this work, we show that this technique can be extended to simultaneously detect changes in the growth and the lipid "flip-flop" and exchange rates induced by a peptide additive on lipid vesicles consisting of DMPC (1,2-dimyristoyl-

Indexed as

Antimicrobial PeptidesLipidsCell MembraneDimyristoylphosphatidylcholineLipid BilayersPhosphatidylethanolaminesScattering, Small AngleAntimicrobial PeptidesDimyristoylphosphatidylcholineLipid BilayersLipidsPhosphatidylethanolamines

Identifiers

PMID34902242
PMCPMC8757467
OpenAlexW4200280653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.