Evidence map›Paper›PMID 34902132›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Integration of DNA Microarray with Clinical and Genomic Data.

Francesca Scionti, Mariamena Arbitrio, Daniele Caracciolo, Licia Pensabene, Pierfrancesco Tassone, Pierosandro Tagliaferri, Maria Teresa Di Martino

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca SciontiInstitute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), Messina, Italy.
Mariamena ArbitrioInstitute for Biomedical Research and Innovation (IRIB-CNR), Section of Catanzaro, Catanzaro, Italy.
Daniele CaraccioloDepartment of Experimental and Clinical Medicine, Magna Græcia University, Catanzaro, Italy.
Licia PensabeneDepartment of Medical and Surgical Sciences, Pediatric Unit, Magna Græcia University, Catanzaro, Italy.
Pierfrancesco TassoneDepartment of Experimental and Clinical Medicine, Magna Græcia University, Catanzaro, Italy.
Pierosandro TagliaferriDepartment of Experimental and Clinical Medicine, Magna Græcia University, Catanzaro, Italy.
Maria Teresa Di MartinoDepartment of Experimental and Clinical Medicine, Magna Græcia University, Catanzaro, Italy. teresadm@unicz.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA microarrays have been widely employed to understand cancer development. This technology is able to measure expression levels of a large numbers of genes or to genotype multiple regions of a genome in a massively parallel experiment. In addition, the detection of methylation patterns and gene copy number variations are also performed. Clinicians began to apply these findings in personalized medicine for the selection of cancer therapy according to the individual's cancer genomic profile. Because cancer is a complex disease it is of great value to integrate microarray data with genomic and clinical data. Here, we presented an overview of DNA microarray technology and discuss about benefits and challenging of microarray data integration.

Indexed as

GenomicsDNA Copy Number VariationsGenomeHumansNeoplasmsOligonucleotide Array Sequence AnalysisDNA microarrayIntegration of omics dataPersonalized medicine

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.