Evidence map›Paper›PMID 34901943›Full record

ArticleNeurotrauma reports2021

Decreases in Dorsal Cervical Spinal Cord White Matter Tract Integrity Are Associated with Elevated Levels of Serum MicroRNA Biomarkers in NCAA Division I Collegiate Football Players.

Linda Papa, Brian Johnson, Alexa E Walter, James R Wilkes, Barbara Knollmann-Ritschel, Manish Bhomia, Semyon M Slobounov

Open access · goldAbstract read
In one paragraph

Article in Neurotrauma reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Linda PapaDepartment of Emergency Medicine, Orlando Regional Medical Center, Orlando, Florida, USA.
Brian JohnsonDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Alexa E WalterDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
James R WilkesDepartment of Kinesiology, Pennsylvania State University, University Park, Pennsylvania, USA.
Barbara Knollmann-RitschelDepartment of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Manish BhomiaDepartment of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Semyon M SlobounovDepartment of Kinesiology, Pennsylvania State University, University Park, Pennsylvania, USA.
Pennsylvania State University · USUniformed Services University of the Health Sciences · USMcGill University · CAThe University of Texas Southwestern Medical Center · USUniversity of Pennsylvania · US

Funding

Biomarkers of Mild and Moderate Traumatic Brain InjuryR01NS057676 · NINDS · ORLANDO REGIONAL HEALTHCARE SYSTEM, INC. · PI PAPA, LINDA · 2008 to 2022
$5.8M
NINDS NIH HHS R01 NS057676
6 · The paper itself

Abstract

This prospective, controlled, observational cohort study assessed the performance of a novel panel of serum microRNA (miRNA) biomarkers relative to findings on cervical spinal cord magnetic resonance imaging (MRI) in collegiate football players. There were 44 participants included in the study: 30 non-athlete control subjects and 14 male collegiate football athletes participating in a Division I Football Bowl Subdivision of the National Collegiate Athletic Association. Diffuse tensor MRI and blood samples were acquired within the week before the athletic season began and within the week after the last game of the season. All miRNAs were significantly higher in athletes regardless of their fractional anisotropy (FA) values (

Indexed as

biomarkerscervical spinal cordconcussionmicroRNAMRIsports

Identifiers

PMID34901943
PMCPMC8655801
OpenAlexW3208816240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.