Evidence map›Paper›PMID 34901781›Full record

ArticlemicroPublication biology2021

Role of the RNA-directed DNA Methylation pathway in the regulation of maternal effects in

Ailén Authier, Pablo Cerdán, Gabriela A Auge

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in microPublication biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ailén AuthierFundación Instituto Leloir, Buenos Aires, Argentina.
Pablo CerdánFundación Instituto Leloir, Buenos Aires, Argentina.
Gabriela A AugeFundación Instituto Leloir, Buenos Aires, Argentina.
Fundación Instituto Leloir · ARUniversity of Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RNA-directed DNA Methylation pathway (RdDM) influences progeny seed responses to different maternal environments. However, its role in the regulation of early traits in response to non-stressful environmental cues across generations, which can potentially affect life cycle adjustment to seasonal changes, has not been explored in detail. Here we show that the RdDM pathway regulates overall germination but, in some instances, it does so depending on the early life maternal environment. Altogether, our results support that epigenetic memory (mediated by RdDM) is regulating intergenerational transmission of environmental information to affect the phenotypic expression of early traits.

Identifiers

PMID34901781
PMCPMC8652579
OpenAlexW4205172444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.