Evidence map›Paper›PMID 34901734›Full record

ArticleImmunomedicine2021

Understanding Immunotherapy Terminology: An Analysis of Provider-Patient Conversations.

Shannon Blee, Bari Rosenberg, Jeffrey M Switchenko, Rachel Hianik, Mary Catherine Thomson, Margie Dixon, Mehmet Asim Bilen, Rebecca D Pentz

Abstract read
In one paragraph

Article in Immunomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shannon BleeWinship Cancer Institute, Emory University.
Bari RosenbergDuke University Medical Center, Emory University.
Jeffrey M SwitchenkoRollins School of Public Health, Emory University.
Rachel HianikUNC Chapel Hill School of Medicine.
Mary Catherine ThomsonMedical College of Georgia.
Margie DixonWinship Cancer Institute, Emory University.
Mehmet Asim BilenWinship Cancer Institute, Emory University.
Rebecca D PentzWinship Cancer Institute, Emory University.

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

backgroundImmunotherapy terminology is complex and can be difficult for patients to understand, threatening informed consent. The aims of this exploratory study are to determine whether patients understand immunotherapy terminology and if the provider defining the term improves patient understanding.

methodsConversations between oncology providers and patients discussing immunotherapy were observed(n=39), and technical terms used were noted. With consent, patients were interviewed post-conversation to assess their understanding of these terms(n=39). Comparisons of the terms were conducted using chi-square tests, Fisher's exact tests, or ANOVA where appropriate.

results'Immunotherapy' was the most difficult for participants to understand with 48.7% (19/39) correctly defining immunotherapy. 'Immunotherapy agents' was understood 53.8% (14/26) of the time. 'Immune system' was well understood (88.5%;23/26). Providers defined immunotherapy in 97.4% of conversations. There was no correlation between having immunotherapy defined in the conversation, and the likelihood of a correct definition (p=0.487). 'Immune system' was defined in 92.3% of conversations (n=26), and defining it in the conversation was correlated with increased patient understanding (p=0.009).

conclusionOur results indicate that patients have difficulty understanding some immunotherapy terminology. Since patient understanding of key terminology is crucial for informed consent and patient care, it is essential to implement interventions to improve understanding.

Indexed as

Immunotherapyimmunotherapy terminologyinformed consentpatient/provider communicationpatient understanding

Identifiers

PMID34901734
PMCPMC8659848

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