Evidence map›Paper›PMID 34901679›Full record

ArticlePain reports

Association between temporal summation and conditioned pain modulation in chronic low back pain: baseline results from 2 clinical trials.

Jiang-Ti Kong, Dokyong Sophia You, Christine Sze Wan Law, Beth D Darnall, James J Gross, Rachel Manber, Sean Mackey

Open access · goldAbstract read
In one paragraph

Article in Pain reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Psychophysics of Pain: A Methodological Introduction.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiang-Ti KongDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Dokyong Sophia YouDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Christine Sze Wan LawDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Beth D DarnallDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
James J GrossDepartment of Psychology, Stanford University, Stanford, CA, USA.
Rachel ManberDepartment of Psychiatry and Behavioral Sciences, Sleep Center, Stanford University School of Medicine, Stanford, CA, California, USA.
Sean MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Stanford Medicine · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTemporal summation (TS) and conditioned pain modulation (CPM) represent different aspects of central pain processing. Their relationship and differential performance within distinct body locations are not well understood.

objectivesTo examine the association between TS and CPM in chronic low back pain and the influence of testing location on this relationship.

methodsWe analyzed

resultsOur models revealed a small association (βs = 0.17,

conclusionResults suggest a modest association between TS and CPM, irrespective of anatomical testing location, demographics, and negative affect. These findings will help improve the methodology and interpretation of TS and CPM measurement in clinical pain populations.

Indexed as

Chronic low back painConditioned pain modulationIndividualized heat stimulusNegative affectTesting locationThermal temporal summation

Identifiers

PMID34901679
PMCPMC8660006
OpenAlexW4200064055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.