Evidence map›Paper›PMID 34901666›Full record

ArticleACS omega2021

Gold Nanorods (AuNRs) and Zeolitic Imidazolate Framework-8 (ZIF-8) Core-Shell Nanostructure-Based Electrochemical Sensor for Detecting Neurotransmitters.

Li Zhao, Guiming Niu, Fucheng Gao, Kaida Lu, Zhiwei Sun, Hui Li, Martina Stenzel, Chao Liu, Yanyan Jiang

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Li ZhaoLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Guiming NiuLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Fucheng GaoLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Kaida LuLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Zhiwei SunLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Hui LiLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.
Martina StenzelSchool of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.ORCID https://orcid.org/0000-0002-6433-4419
Chao LiuDepartment of Oromaxillofacial Head and Neck Oncology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital, Shanghai 200011, P. R. China.
Yanyan JiangLiquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China.ORCID https://orcid.org/0000-0002-7866-4689
Shandong University · CNShanghai Jiao Tong University · CNUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of novel electrode materials for rapid and sensitive detection of neurotransmitters in the human body is of great significance for early disease diagnosis and personalized therapy. Herein, gold nanorod@zeolitic imidazolate framework-8 (AuNR@ZIF-8) core-shell nanostructures were prepared by controlled encapsulation of gold nanorods within a ZIF-8 assembly. The designed AuNR@ZIF-8 nanostructures have uniform morphology, good dispersion, a large specific surface area, and an average size of roughly 175 nm. Compared with individual ZIF-8 and AuNR-modified electrodes, the obtained core-shell-structured AuNR@ZIF-8 nanocomposite structure-modified electrode shows excellent electrocatalytic performance in the determination of dopamine (DA) and serotonin (ST). The designed AuNR@ZIF-8 exhibited a wide linear range of 0.1-50 μM and low detection limit (LOD, 0.03 μM, S/N = 3) for the determination of DA, as well as a linear range of 0.1-25 μM and low LOD (0.007 μM, S/N = 3) for monitoring ST. The improved performance is attributed to the synergistic effect of the high conductivity of AuNRs and multiple catalytic sites of ZIF-8. The good electroanalytical ability of AuNR@ZIF-8 for detection of DA and ST can provide a guide to efficiently and rapidly monitor other neurotransmitters and construct novel electrochemical sensors.

Identifiers

PMID34901666
PMCPMC8655944
OpenAlexW3215478703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.