Evidence map›Paper›PMID 34901573›Full record

ArticleKidney international reports2021

Renal Prognosis in Children With Tubulointerstitial Nephritis and Uveitis Syndrome.

Agnès Chevalier, Claire Duflos, Stephanie Clave, Olivia Boyer, Julien Hogan, Annie Lahoche, Stephane Decramer, Françoise Broux, Isabelle Vrillon, Emma Allain-Launay and 15 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 1 country.

Agnès ChevalierService de Néphrologie pédiatrique, Centre Hospitalier Universitaire Montpellier, centre de référence maladies rénales rares du sud-ouest SORARE, Université de Montpellier-Filière ORKiD, Montpellier, France.
Claire DuflosUnité de Recherche Clinique et Epidémiologique, Centre Hospitalier Universitaire Montpellier, Université de Montpellier, Montpellier, France.
Stephanie ClaveService de Pédiatrie multidisciplinaire, Centre Hospitalier Universitaire Marseille, Marseille, France.
Olivia BoyerService de Néphrologie pédiatrique, Centre de référence MARHEA, Hôpital Necker-Enfants Malades, Assistance Publique-HóPitaux De Paris, Institut Imagine, Université de Paris, Paris, France.
Julien HoganService de Néphrologie-Hémodialyse, Assistance Publique-HóPitaux De Paris Hôpital Robert-Debré, Paris, France.
Annie LahocheService de Pédiatrie-Unité de Néphrologie, Centre Hospitalier Régional Universitaire Lille, Lille, France.
Stephane DecramerService de Pédiatrie-Néphrologie, médecine interne et hypertension, Centre des maladies rénales rares du sud-ouest SORARE, Centre Hospitalier Universitaire Toulouse, Toulouse, France.
Françoise BrouxDépartement de pédiatrie médicale, Centre Hospitalier Universitaire Rouen, Rouen, France.
Isabelle VrillonService de Pédiatrie, Centre Hospitalier Universitaire Nancy, Nancy, France.
Emma Allain-LaunayService de Néphrologie et immunologie clinique, Centre Hospitalier Universitaire Nantes, Nantes, France.
Justine BacchettaCentre de référence des maladies rénales rares Néphrogones, Service de Néphrologie Rhumatologie Dermatologie Pédiatriques, Hôpital Femme Mère Enfant, Bron, Hospices Civils de Lyon, Lyon, France.
Corentin TanneCentre de référence des maladies rénales rares Néphrogones, Service de Néphrologie Rhumatologie Dermatologie Pédiatriques, Hôpital Femme Mère Enfant, Bron, Hospices Civils de Lyon, Lyon, France.
Lise AllardService de Pédiatrie, Unité de Néphrologie pédiatrique, centre de référence maladies rénales rares du sud-ouest SORARE, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.
Sylvie CloarecService de Néphrologie-hémodialyse pédiatrique, Centre Hospitalier Régional Universitaire Tours, Tours, France.
Christine PietrementService de Pédiatrie générale et spécialisée, Centre Hospitalier Universitaire Reims, Reims, France.
Guylhene Bourdat-MichelService de Pédiatrie-Néphrologie pédiatrique, Centre Hospitalier Universitaire Grenoble, Grenoble, France.
Djamal DjeddiService de Pédiatrie Médicale, Pôle Femme Couple Enfant, Centre Hospitalier Universitaire Amiens, Amiens, France.
Olivier DunandService de Néphrologie pédiatrique, Centre Hospitalier Universitaire La Réunion, Réunion, France.
Camille FaudeuxService de néphrologie pédiatrique, Centre Hospitalier Universitaire Nice, Nice, France.
François NobiliService de pédiatrique 2, néphrologie-réanimation infantile, Centre Hospitalier Régional Universitaire Besançon, Besançon, France.
Sophie TaqueService de Pédiatre, Centre Hospitalier Universitaire Rennes, Rennes, France.
Tim UlinskiService de néphrologie pédiatrique, centre de référence MARHEA, Hôpital Armand-Trousseau, Assistance Publique-Hópitaux De Paris, Sorbonne Université, Paris, France.
Ariane ZaloszycService de Néphrologie pédiatrique, Centre Hospitalier Universitaire Strasbourg, Strasbourg, France.
Denis MorinService de Néphrologie pédiatrique, Centre Hospitalier Universitaire Montpellier, centre de référence maladies rénales rares du sud-ouest SORARE, Université de Montpellier-Filière ORKiD, Montpellier, France.
Marc FilaService de Néphrologie pédiatrique, Centre Hospitalier Universitaire Montpellier, centre de référence maladies rénales rares du sud-ouest SORARE, Université de Montpellier-Filière ORKiD, Montpellier, France.
Centre Hospitalier Universitaire de Montpellier · FRHôpital Femme Mère Enfant · FRAssistance Publique Hôpitaux de Marseille · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Grenoble · FRCentre Hospitalier Universitaire de La Réunion · FRCentre Hospitalier Universitaire de Lille · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Nice · FRCentre Hospitalier Universitaire de Reims · FRCentre Hospitalier Universitaire de Rouen · FRCentre Hospitalier Universitaire de Toulouse · FRCentre Hospitalier Universitaire de Tours · FRHôpital Necker-Enfants Malades · FRHôpital Pontchaillou · FRHôpitaux Universitaires de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTubulointerstitial nephritis (TIN) and uveitis (TINU) syndrome is a rare disease. The renal prognosis is generally thought to be better in children with TINU syndrome than in adults. However, data are scarce. We aimed to investigate the long-term renal prognosis in a French cohort of children with TINU syndrome.

methodsWe performed a national retrospective study including 23 French pediatric nephrology centers enrolling patients with TINU syndrome diagnosed between January 2000 and December 2018.

resultsA total of 46 patients were included (52% female, median age 13.8 years). At diagnosis of TIN, the median estimated glomerular filtration rate (eGFR) was 30.6 ml/min per 1.73 m

conclusionIn our study, nearly half of the patients had renal sequelae at last follow-up. Given the possible progression to chronic kidney disease, long-term monitoring of children with TINU syndrome is mandatory. Approximately a quarter of the children had asymptomatic uveitis suggesting all children presenting with TIN should undergo systematic ophthalmologic screening even in the absence of ocular signs.

Indexed as

chronic kidney failureDobrin’s syndromeoutcomepediatrictubulointerstitial nephritis and uveitis syndrome

Identifiers

PMID34901573
PMCPMC8640547
OpenAlexW3204995440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.