Evidence map›Paper›PMID 34901522›Full record

ArticleAmerican journal of ophthalmology case reports2021

Choroidal neovascularization complicating sclerochoroidal calcifications.

Maurizio Battaglia Parodi, Alessandro Arrigo, Adelaide Pina, Francesca Calcagno, Alessio Antropoli, Rashid Hassan Farah, Francesco Bandello, Ahmad M Mansour

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Maurizio Battaglia ParodiDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Alessandro ArrigoDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Adelaide PinaDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Francesca CalcagnoDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Alessio AntropoliDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Rashid Hassan FarahDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Francesco BandelloDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.
Ahmad M MansourDepartment of Ophthalmology, American University of Beirut, Rafic Hariri University Hospital, P.O. Box 113-6044, Beirut, Lebanon.
Vita-Salute San Raffaele University · ITRafik Hariri University Hospital · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSclerochoroidal calcifications (SCC) are rare conditions characterized by unifocal or multifocal well-defined scleral deposits of calcium. The present study describes two cases of SCC complicated by the onset of choroidal neovascularization (CNV).

methodFive patients affected by SCC were enrolled in the study and two cases were complicated by CNV. Both patients underwent complete ophthalmic examination with multimodal imaging including optical coherence tomography angiography (OCTA).

resultsIn the two patients with CNV (1 male), BCVA was 20/40 and 20/50 in the affected eyes. Fundus examination revealed an irregular yellow-white lesion close to the superotemporal arcade in both patients, with exudation. The diagnosis of CNV was performed by means of fluorescein angiography in one patient and OCTA in the other patient. The patients received a total of 3 and 9 ranibizumab injections respectively over a six-year follow-up, reaching a final BCVA of 20/25 in both patients with stabilization of the CNV.

conclusionsSCC may be complicated by CNV, with good management obtained by intravitreal anti-VEGF injections.

Indexed as

Choroidal neovascularizationFAFMultimodal imagingOCTOCTASclerochoroidal calcification

Identifiers

PMID34901522
PMCPMC8640104
OpenAlexW3217756246

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.