Evidence map›Paper›PMID 34901459›Full record

ArticleOpen medicine (Warsaw, Poland)2021

circATP2A2 promotes osteosarcoma progression by upregulating MYH9.

Xin Cao, Xianfeng Meng, Peng Fu, Lin Wu, Zhen Yang, Huijin Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The roles of glycolysis in osteosarcoma.Frontiers in pharmacology · 2022
    Review
  5. Caudatin Inhibits the Proliferation, Invasion, and Glycolysis of Osteosarcoma Cells via the Wnt/Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xin CaoDepartment of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Xianfeng MengDepartment of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Peng FuDepartment of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Lin WuDepartment of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Zhen YangDepartment of Trauma and Orthopaedics, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Huijin ChenDepartment of Clinical Laboratory, Shengli Oilfield Central Hospital, No. 31, Jinan Road, Dongying, 257000, Shandong, China.
Shengli Oilfield Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is a highly metastatic primary malignant tumor. CircRNA hsa_circ_0028173 (circATP2A2) has been uncovered to be related to the advancement of OS. However, the biological role of circATP2A2 in OS has not been validated. circATP2A2 and MYH9 were upregulated while miR-335-5p was downregulated in OS. OS patients with high circATP2A2 expression displayed a shorter overall survival and the area under curve of circATP2A2 was 0.77, manifesting that circATP2A2 might be a diagnostic and prognostic biomarker. circATP2A2 silencing repressed OS cell proliferation and glycolysis

Indexed as

circATP2A2miR-335-5pMYH9OS

Identifiers

PMID34901459
PMCPMC8630393
OpenAlexW3217378727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.