Evidence map›Paper›PMID 34901051›Full record

ReviewFrontiers in medicine2021

Unusual Reactions to Hymenoptera Stings: Current Knowledge and Unmet Needs in the Pediatric Population.

Riccardo Castagnoli, Mattia Giovannini, Francesca Mori, Simona Barni, Luca Pecoraro, Stefania Arasi, Francesca Saretta, Carla Mastrorilli, Lucia Liotti, Lucia Caminiti and 3 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Hymenoptera venom allergy in children.Italian journal of pediatrics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Riccardo CastagnoliDepartment of Pediatrics, Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Mattia GiovanniniAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Francesca MoriAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Simona BarniAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Luca PecoraroDepartment of Medicine, University of Verona, Policlinico GB Rossi, Verona, Italy.
Stefania ArasiTranslational Research in Pediatric Specialities Area, Division of Allergy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Carla MastrorilliPediatric Unit and Emergency, University Hospital Consortium Corporation Polyclinic of Bari, Pediatric Hospital Giovanni XXIII, Bari, Italy.
Lucia LiottiDepartment of Pediatrics, Salesi Children's Hospital, AOU Ospedali Riuniti Ancona, Ancona, Italy.
Lucia CaminitiDepartment of Human Pathology in Adult and Development Age "Gaetano Barresi," Allergy Unit, Department of Pediatrics, AOU Policlinico Gaetano Martino, Messina, Italy.
Gunter Johannes SturmDepartment of Dermatology and Venerology, Medical University of Graz, Graz, Austria.
Gian Luigi MarsegliaDepartment of Pediatrics, Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Elio NovembreAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Meyer Children's Hospital · ITUniversity of Pavia · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Ortopedico Gaetano Pini · ITMedical University of Graz · ATOspedale di Latisana · ITOspedale Pediatrico Giovanni XXIII · ITOspedali Riuniti di Ancona · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hymenoptera stings are generally well-tolerated and usually cause limited local reactions, characterized by self-resolving erythema and edema associated with pain. However, Hymenoptera stings can induce immediate and delayed hypersensitivity reactions. In addition to these manifestations, unusual reactions to Hymenoptera stings have been reported. The latter are defined as unusual because of their atypical characteristics. They may differ from classical hypersensitivity reactions due to the stings' particular localization and the unusual involvement of one or more specific organs. Although unusual reactions to Hymenoptera stings are infrequent, it is essential for clinicians to know the possible related clinical manifestations. Here, we review the available literature and propose a diagnostic and management algorithm. At present, there are no defined guidelines for most of the unusual reactions to Hymenoptera stings, which should be managed in a tailored way according to the specifical clinical manifestations presented by the patients. Further studies are needed to better define these conditions and the underlying pathogenetic mechanisms to improve the diagnostic and therapeutic approach.

Indexed as

anaphylaxischildrenHymenoptera venom allergyIgEunusual reactionsvenom immunotherapy

Identifiers

PMID34901051
PMCPMC8661053
OpenAlexW3215845005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.