Evidence map›Paper›PMID 34901022›Full record

ArticleFrontiers in cell and developmental biology2021

Regeneration of Planarian Auricles and Reestablishment of Chemotactic Ability.

Eugene Matthew P Almazan, Joseph F Ryan, Labib Rouhana

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. The Sensory Basis of Planarian Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  2. eLife · 2025
    Article
  3. bioRxiv : the preprint server for biology · 2025
    Article
  4. The Multiscale Wisdom of the Body: Collective Intelligence as a Tractable Interface for Next-Generation Biomedicine.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  5. Article
  6. Exploring the potential ofCurrent research in toxicology · 2025
    Article
  7. The role ofbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. The Role ofIntegrative organismal biology (Oxford, England) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eugene Matthew P AlmazanDepartment of Biological Sciences, Wright State University, Dayton, OH, United States.
Joseph F RyanWhitney Laboratory of Marine Biosciences, University of Florida, St. Augustine, FL, United States.
Labib RouhanaDepartment of Biological Sciences, Wright State University, Dayton, OH, United States.
Wright State University · USUniversity of Florida · US

Funding

Discovery of germline genes and regulatory networks in planariansR15HD082754 · NICHD · WRIGHT STATE UNIVERSITY · PI ROUHANA, LABIB · 2014 to 2024
$1.3M
NICHD NIH HHS R15 HD082754
6 · The paper itself

Abstract

Detection of chemical stimuli is crucial for living systems and also contributes to quality of life in humans. Since loss of olfaction becomes more prevalent with aging, longer life expectancies have fueled interest in understanding the molecular mechanisms behind the development and maintenance of chemical sensing. Planarian flatworms possess an unsurpassed ability for stem cell-driven regeneration that allows them to restore any damaged or removed part of their bodies. This includes anteriorly-positioned lateral flaps known as auricles, which have long been thought to play a central role in chemotaxis. The contribution of auricles to the detection of positive chemical stimuli was tested in this study using

Indexed as

auricleschemotaxisGirardia dorotocephalaneoblastplanarianregenerationstem cells

Identifiers

PMID34901022
PMCPMC8662385
OpenAlexW3215036989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.