Evidence map›Paper›PMID 34901011›Full record

ArticleFrontiers in cell and developmental biology2021

The Lung Elastin Matrix Undergoes Rapid Degradation Upon Adult Loss of

Mu-Hang Li, Leilani M Marty-Santos, Paul R van Ginkel, Aubrey E McDermott, Andrew J Rasky, Nicholas W Lukacs, Deneen M Wellik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Toward a cell-type-specific lung HOX code.Frontiers in cell and developmental biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Characterization of a novel Hoxa5eGFP mouse line.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  6. Article
  7. Hox genes in development and beyond.Development (Cambridge, England) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mu-Hang LiGenetics Training Program, University of Wisconsin-Madison, Madison, WI, United States.
Leilani M Marty-SantosDepartment of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Paul R van GinkelDepartment of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Aubrey E McDermottDepartment of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Andrew J RaskyDepartment of Pathology, University of Michigan, Ann Arbor, MI, United States.
Nicholas W LukacsDepartment of Pathology, University of Michigan, Ann Arbor, MI, United States.
Deneen M WellikDepartment of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
University of Wisconsin–Madison · USUniversity of Michigan–Ann Arbor · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
Hox5 gene regulation of lung fibrobroblasts and distal lung extracellular matrixR01HL144086 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WELLIK, DENEEN M · 2018 to 2021
$1.8M
Characterization of the role of mesenchymal Hox5 genes in alveologenesisF32HL140969 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MARTY-SANTOS, LEILANI MARIE · 2018 to 2020
$139k
NHLBI NIH HHS F32 HL140969NHLBI NIH HHS R01 HL144086NIGMS NIH HHS T32 GM007133
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brochopulmonary dysplasiadistal lung fibroblastsemphysemaextracellular matrixHox geneslung homeostasislung macrophages

Identifiers

PMID34901011
PMCPMC8662386
OpenAlexW3214738083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.