Evidence map›Paper›PMID 34900969›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Bioclickable Mussel-Derived Peptides With Immunoregulation for Osseointegration of PEEK.

Huan Zhao, Xiaokang Wang, Wen Zhang, Lin Wang, Can Zhu, Yingkang Huang, Rongrong Chen, Xu Chen, Miao Wang, Guoqing Pan and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Huan ZhaoDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Xiaokang WangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Wen ZhangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Lin WangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Can ZhuDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Yingkang HuangDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Rongrong ChenDepartment of Pediatrics, The Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong University, Nantong, China.
Xu ChenInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, Zhenjiang, China.
Miao WangInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, Zhenjiang, China.
Guoqing PanInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, Zhenjiang, China.
Qin ShiDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Xichao ZhouDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Orthopaedic Institute of Soochow University, Suzhou, China.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNJiangsu University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyether ether ketone (PEEK)-based biomaterials have been widely used in the field of spine and joint surgery. However, lack of biological activity limits their further clinical application. In this study, we synthesized a bioclickable mussel-derived peptide Azide-DOPA

Indexed as

bio-orthogonal reactionbone morphogenetic protein 2 functional peptidesclickable mussel-biomimetic peptideFOXP3+ regulatory T cellsosseointegrationPEEK

Identifiers

PMID34900969
PMCPMC8652040
OpenAlexW3217318668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.