Evidence map›Paper›PMID 34900939›Full record

ArticleFrontiers in chemistry2021

Ferritin Conjugates With Multiple Clickable Amino Acids Encoded by C-Terminal Engineered Pyrrolysyl-tRNA Synthetase.

Yi-Hui Wang, Mu-Lung Jian, Pei-Jung Chen, Jo-Chu Tsou, Le P Truong, Yane-Shih Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Chemical reviews · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yi-Hui WangInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Mu-Lung JianInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Pei-Jung ChenInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Jo-Chu TsouInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Le P TruongInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Yane-Shih WangInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
National Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the application of expanding genetic codes in developing protein cage-based delivery systems. The evolved Methanosarcina mazei pyrrolysyl-tRNA synthetase (PylRS)•tRNA

Indexed as

amber suppression efficiencydrug deliveryferritin-drug conjugatesp-Azido-l-phenylalaninepyrrolysyl-tRNA synthetasestrain-promoted azide-alkyne cycloaddition

Identifiers

PMID34900939
PMCPMC8655692
OpenAlexW3217290852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.