ReviewJournal of diabetes and metabolic disorders2021
The conceptual and practical definitions of frailty in older adults: a systematic review.
Review in Journal of diabetes and metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between frailty and adverse outcomes after cardiac resynchronization therapy: a systematic review and meta-analysis.European geriatric medicine · 2025Pooled it
- A Systematic Review of Frailty Interventions in Community-Based Low and Middle-Income Settings.International journal of public health · 2025Pooled it
- Frailty and long-term survival of patients with ovarian cancer: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Exploring educational needs on frailty outside geriatrics: a survey of European Union of Medical Specialists' bodies.European geriatric medicine · 2026Article
- Australian Consensus Statement on the Prevention and Management of Frailty Among Community-Dwelling Older Adults: A Modified Delphi Study.The Medical journal of Australia · 2026Article
- Sleep quality and its relationship with physical activity and frailty syndrome among hospitalized older adults in North Iran.African health sciences · 2026Article
- Prehabilitation for muscle wasting in cancer: do definitions matter?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Review
- Perceptions of Frailty in Long-Term Care.Canadian geriatrics journal : CGJ · 2025Article
- Article
- Frailty in Geriatrics: A Critical Review with Content Analysis of Instruments, Overlapping Constructs, and Challenges in Diagnosis and Prognostic Precision.Journal of clinical medicine · 2025Review
- Building Research Infrastructure to Address Psychosocial Frailty and Reach Underserved Aging Populations.Journal of psychosocial nursing and mental health services · 2025Article
- Frailty in clinical drug trials: Frailty assessments, subgroup analyses and outcomes.British journal of clinical pharmacology · 2025Review
- Connectome-based predictive modeling of grip strength: a marker of physical frailty.Frontiers in neuroscience · 2025Article
- Risk prediction model of physical frailty for a rural older population: a cross-sectional study in Hunan Province, China.Frontiers in public health · 2025Article
- Association of cognitive function with frailty, nutritional status, and quality of life in older adults with mild cognitive impairment.PloS one · 2025Article
- Development and content validity of the evaluation of multidimensional functioning and risks in aging scale.PeerJ · 2025Article
- Understanding frailty and its opposites from community-dwelling older peoples' perspectives: A phenomenological qualitative study.International journal of nursing studies advances · 2024Article
- Utilization and Impact of a Radiation Nursing Clinic to Address Acute Care Needs for Patients with Gynecologic Cancers.Current oncology (Toronto, Ont.) · 2024Article
- Accelerated Aging in Cancer Survivors: Cellular Senescence, Frailty, and Possible Opportunities for Interventions.International journal of molecular sciences · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to review and extract all publications containing concepts related to definitions of frailty and categorize them.
methodsA total of six electronic databases (PubMed, Ovid web, Web of Science, Scopus, Embase, Cochrane Library, and ProQuest) were searched to identify studies that introduced a definition of frailty up to October 2018. No language restrictions were imposed.
resultsTotally, 104,370 papers were found in the initial search and finally 68 papers were included. Of these, 21 studies provided a conceptual definition and 50 original articles also 9 review articles provided a practical definition. Moreover, 12 papers had both definitions of frailty. Of them, 62 were published in English, 2 in Portuguese, 1 in Japanese, 2 in Korean, and 1 in German languages.
conclusionMany screening tools have been developed but neither of them can cover a wide range of parameters at the same time, nor do they have simplicity in the execution. It is important to note that although a more or less general consensus on one single definition might be expected, we believe that the elderly population is too heterogeneous to allow a tool to address it as a whole, and such a definition may even be impossible. Therefore, in the absence of a "Gold Standard" definition, it is suggested to seek accurate knowledge of the strengths and weaknesses of each definition and choose the most appropriate definition and the most effective evaluation tool according to the purpose of the research and the characteristics of the older population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.