Evidence map›Paper›PMID 34900796›Full record

ArticleJournal of diabetes and metabolic disorders2021

Systematisation of biological protectors for managing the metabolic syndrome development.

Valery V Benberin, Ainur S Sibagatova, Almagul A Nagimtayeva, Kamshat M Akhmetova, Tamara A Voshchenkova

RetractedAbstract readRetracted Publication
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Valery V BenberinAdministrative Department, Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Republic of Kazakhstan.
Ainur S SibagatovaSector оf Clinical Research, Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Republic of Kazakhstan.
Almagul A NagimtayevaGerontology Centre, Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Republic of Kazakhstan.
Kamshat M AkhmetovaGerontology Centre, Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Republic of Kazakhstan.
Tamara A VoshchenkovaGerontology Centre, Medical Centre Hospital of President's Affairs Administration of the Republic of Kazakhstan, 010000, 80 Mangilik El Ave., Nur-Sultan, Republic of Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome (MS) is becoming a major health risk in the world. Disorders of homeostasis are a trigger for MS and subsequent cardiometabolic diseases (CMDs). Its physiological role can be supported by biological protectors (BP). The purpose of this study is to develop a BP system for managing the MS development.

methodsWithin the framework of the case-control study, 3000 participants aged 20-60 years formed 2 groups: the main group and the control group.

resultsThe study compared traditional markers of oxidative stress, chronic inflammation, and insulin resistance, which reflect the state of homeostasis. The BP system, proposed based on the concept of maintaining homeostasis, offers the following points for investigating the possibilities of therapeutic intervention: confronting dysregulation of homeostasis, resisting chronic inflammation and oxidative stress, resisting the consequences of disturbed homeostasis. This approach not only contributed to the understanding of general biological processes, but also provided a targeted search and development of BP to maintain the stability of homeostasis with MS.

conclusionsThe study results provided insight into new opportunities in the MS management.

Indexed as

BioprotectorsCardiometabolic diseasesHomeostasisRegulation of homeostasis

Identifiers

PMID34900796
PMCPMC8630288

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.