Evidence map›Paper›PMID 34900755›Full record

ArticleFrontiers in cellular and infection microbiology2021

Profiling the Quality and Quantity of Naturally Induced Antibody Responses Against Pfs230 and Pfs48/45 Among Non-Febrile Children Living in Southern Ghana: A Longitudinal Study.

Fermin K Broni, Festus K Acquah, Dorcas Obiri-Yeboah, Evans K Obboh, Esther Sarpong, Linda E Amoah

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fermin K BroniDepartment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.
Festus K AcquahImmunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Dorcas Obiri-YeboahDepartment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.
Evans K ObbohDepartment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.
Esther SarpongDepartment of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
Linda E AmoahImmunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
University of Cape Coast · GHNoguchi Memorial Institute for Medical Research · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A clear understanding of the properties of naturally induced antibody responses against transmission-blocking vaccine candidates can accelerate the understanding of the development of transmission-blocking immunity. This study characterized the naturally induced IgG responses against two leading transmission-blocking vaccine antigens, Pfs230 and Pfs48/45, in non-febrile children living in Simiw, Ghana. Consecutive sampling was used to recruit 84 non-febrile children aged from 6 to 12 years old into the 6-month (November 2017 until May 2018) longitudinal study. Venous blood (1 ml) was collected once every 2 months and used to determine hemoglobin levels,

Indexed as

Antibody FormationMalaria, FalciparumAdolescentAntibodies, ProtozoanAntigens, ProtozoanChildGhanaHumansLongitudinal StudiesPlasmodium falciparumProtozoan ProteinsAntibodies, ProtozoanAntigens, ProtozoanProtozoan Proteinsantibody levelsgametocyteP. falciparumpolymerase chain reaction (PCR)relative avidity

Identifiers

PMID34900755
PMCPMC8656302
OpenAlexW3217184363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.