Evidence map›Paper›PMID 34900637›Full record

ArticleJournal of reproduction & infertility

Correlation of Sperm Mitochondrial DNA 7345

Mazhar Salim Al Zoubi, Ali M Al-Talafha, Emad Al Sharu, Bahaa Al-Trad, Ayman Alzu'bi, Manal Issam AbuAlarjah, Qasem Shehab, Mohammad Alsmadi, Khalid M Al-Batayneh

Open access · greenAbstract read
In one paragraph

Article in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Novel Variants in Sperm Mitochondrial Cytochrome C Oxidase II (Current issues in molecular biology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mazhar Salim Al ZoubiDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Ali M Al-TalafhaDepartment of Biological Sciences, Faculty of Science, Yarmouk University, Irbid, Jordan.
Emad Al SharuKing Hussein Medical Centre, Royal Medical Services, Amman, Jordan.
Bahaa Al-TradDepartment of Biological Sciences, Faculty of Science, Yarmouk University, Irbid, Jordan.
Ayman Alzu'biDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Manal Issam AbuAlarjahDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Qasem ShehabDepartment of Clinical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Mohammad AlsmadiDepartment of Gynecology and Reproductive Medicine, Faculty of Medicine, Saarland University, Saarbrücken, Germany.
Khalid M Al-BataynehDepartment of Biological Sciences, Faculty of Science, Yarmouk University, Irbid, Jordan.
Yarmouk University · JOKing Hussein Medical Center · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlterations in sperm mitochondrial DNA (mtDNA) affect the functions of some OXPHOS proteins which will affect sperm motility and may be associated with asthenozoospermia. The purpose of this study was to investigate the correlation between 7599-

methodsSemen specimens from 200 men including 121 infertile and 79 healthy individuals were collected at the Royal Jordanian Medical Services In-vitro fertilization (IVF) units. The mtDNA was extracted followed by mtDNA amplification. Polymerase chain reaction (PCR) was conducted for the target sequences, then DNA sequencing was performed for the PCR products. Chi-square, Fisher's and Spearman's tests were used to calculate the correlation.

resultsThe results showed a significant correlation between the presence of 7599-

conclusionWe demonstrated a significant correlation between asthenozoospermia and the 7599-

Indexed as

AsthenozoospermiaGene deletionMale infertilityMitochondrial DNASperm motility

Identifiers

PMID34900637
PMCPMC8607879
OpenAlexW3178011295

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.