Evidence map›Paper›PMID 34900593›Full record

ArticleMolecular genetics and metabolism reports2021

Untreated PKU patients without intellectual disability:

K Klaassen, M Djordjevic, A Skakic, B Kecman, R Drmanac, S Pavlovic, M Stojiljkovic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Diseases (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

K KlaassenInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
M DjordjevicMother and Child Health Care Institute of Serbia "Dr Vukan Cupic", Belgrade, Serbia.
A SkakicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
B KecmanMother and Child Health Care Institute of Serbia "Dr Vukan Cupic", Belgrade, Serbia.
R DrmanacComplete Genomics Incorporated, San Jose, California 95134, USA.
S PavlovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
M StojiljkovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
University of Belgrade · RSInstitute of Public Health of Serbia · RSBGI Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenylketonuria (PKU) is an inborn error of metabolism caused by variants in the phenylalanine hydroxylase (

Indexed as

ASD, autism spectrum disorderscPKU, classical phenylketonuriaIntellectual disabilityIQ, intelligence quotientLate-diagnosedModifier geneNGS, next generation sequencingNMDA, N-methyl D-aspartatePAH, phenylalanine hydroxylasePhenylketonuriaPKU, phenylketonuriaSHANKUntreated

Identifiers

PMID34900593
PMCPMC8639809
OpenAlexW3216468607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.