Evidence map›Paper›PMID 34900518›Full record

ArticleAdvanced materials interfaces2021

Graphene-Based Femtogram-Level Sensitive Molecularly Imprinted Polymer of SARS-CoV-2.

Seyyed Alireza Hashemi, Sonia Bahrani, Seyyed Mojtaba Mousavi, Navid Omidifar, Nader Ghaleh Golab Behbahan, Mohammad Arjmand, Seeram Ramakrishna, Kamran Bagheri Lankarani, Mohsen Moghadami, Mohammad Firoozsani

Open access · bronzeAbstract read
In one paragraph

Article in Advanced materials interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Seyyed Alireza HashemiNanomaterials and Polymer Nanocomposites Laboratory School of Engineering University of British Columbia Kelowna BC V1V 1V7 Canada.
Sonia BahraniHealth Policy Research Center Health Institute Shiraz University of Medical Sciences Shiraz 71348-45794 Iran.
Seyyed Mojtaba MousaviDepartment of Chemical Engineering National Taiwan University of Science and Technology Taipei City 310635 Taiwan.
Navid OmidifarClinical Education Research Center Shiraz University of Medical Sciences Shiraz 71348-14336 Iran.
Nader Ghaleh Golab BehbahanDepartment of Poultry Disease Razi Vaccine and Serum Research Institute Shiraz Branch Agricultural Research, Education and Extension Organization (AREEO) Shiraz 7188843568 Iran.
Mohammad ArjmandNanomaterials and Polymer Nanocomposites Laboratory School of Engineering University of British Columbia Kelowna BC V1V 1V7 Canada.
Seeram RamakrishnaDepartment of Mechanical Engineering Center for Nanofibers and Nanotechnology National University of Singapore Singapore 117576 Singapore.ORCID https://orcid.org/0000-0001-8479-8686
Kamran Bagheri LankaraniHealth Policy Research Center Health Institute Shiraz University of Medical Sciences Shiraz 71348-45794 Iran.
Mohsen MoghadamiHealth Policy Research Center Health Institute Shiraz University of Medical Sciences Shiraz 71348-45794 Iran.
Mohammad FiroozsaniMember of Board of Trustees Zand Institute of Higher Education Shiraz 7188773489 Iran.
Shiraz University of Medical Sciences · IRUniversity of British Columbia · CANational Taiwan University of Science and Technology · TWNational University of Singapore · SGRazi Vaccine and Serum Research Institute · IRSadra Institute Of Higher Education · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid distribution of viral-induced diseases and weaknesses of common diagnostic platforms for accurate and sensitive identification of infected people raises an urgent demand for the design and fabrication of biosensors capable of early detection of viral biomarkers with high specificity. Accordingly, molecularly imprinted polymers (MIPs) as artificial antibodies prove to be an ideal preliminary detection platform for specific identification of target templates, with superior sensitivity and detection limit (DL). MIPs detect the target template with the "lock and key" mechanism, the same as natural monoclonal antibodies, and present ideal stability at ambient temperature, which improves their practicality for real applications. Herein, a 2D MIP platform consisting of decorated graphene oxide with the interconnected complex of polypyrrole-boronic acid is developed that can detect the trace of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen in aquatic biological samples with ultrahigh sensitivity/specificity with DL of 0.326 and 11.32 fg mL

Indexed as

graphenemolecularly imprinted polymerspolypyrroleSARS‐CoV‐2ultrasensitive detection of viral antigens

Identifiers

PMID34900518
PMCPMC8646612
OpenAlexW3211501164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.