Evidence map›Paper›PMID 34900504›Full record

ArticleCureus2021

Implementing the First Outpatient Parenteral Antimicrobial Therapy (OPAT) Program to Utilize Disposable Elastomeric Pumps in the Gulf Region: Results From a Tertiary Teaching Hospital in the Kingdom of Saudi Arabia.

Ahmed Zikri, Hassan Al-Faraj, Nabil Kamas, Jumaan AlZahrani, Hisham BuKhamseen, Wasan Alshahoub, Arlene Beltran, Dalia Fatih, Zainab AlMusa

Open access · diamondAbstract read
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Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ahmed ZikriDepartment of Pharmacy, King Fahad Specialist Hospital, Dammam, SAU.
Hassan Al-FarajDepartment of Internal Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Nabil KamasDepartment of Pharmacy, King Fahad Specialist Hospital, Dammam, SAU.
Jumaan AlZahraniDepartment of Pharmacy, King Fahad Specialist Hospital, Dammam, SAU.
Hisham BuKhamseenDepartment of Pharmacy, King Fahad Specialist Hospital, Dammam, SAU.
Wasan AlshahoubDepartment of Pharmacy, King Fahad Specialist Hospital, Dammam, SAU.
Arlene BeltranDepartment of Home Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Dalia FatihDepartment of Home Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Zainab AlMusaDepartment of Internal Medicine/Infectious Diseases, King Fahad Specialist Hospital, Dammam, SAU.
King Fahad Specialist Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives To describe the implementation process, safety, and efficacy outcomes, as well as cost-effectiveness, of the first outpatient parenteral antimicrobial therapy (OPAT) program to utilize disposable elastomeric pumps in the Kingdom of Saudi Arabia and the entire Gulf region. Methods This OPAT program was initiated in May 2018 and was administered through a multidisciplinary team that included the home medicine department, pharmacy department, nursing department, and the infectious diseases service. The device used was the Intermate® (Baxter, Deerfield, Illinois) elastomeric pump. After consultation with an infectious diseases physician, eligible patients were discharged home to complete the remainder of their antimicrobial treatment, which was self-administered via the elastomeric devices. Results From May 2018 to December 2019, 47 patients received 55 courses of OPAT via the new program. A total of 2,869 pumps were used during that period to provide 927 days of antimicrobial therapy in the home setting. Most patients completed the program successfully with no reported significant OPAT-related complications such as catheter-related infections. Four patients were re-admitted for relapse of infections and one patient was re-admitted for colistin-induced nephrotoxicity. No mortality was reported for any patient during OPAT treatment and 30 days after program completion. Conclusions The implementation of this novel OPAT program was safe, effective, and offered significant cost-savings to our institution. The entire process was very dynamic and was centered around proper patient selection and education as well as excellent communication between patients and the entire multidisciplinary team involved in the program. We hope that these results will encourage other institutions in the region to implement similar OPAT programs to alleviate the existing bed crisis due to the ongoing COVID-19 pandemic.

Indexed as

antibioticselastomeric pumpshome health careinfectionsoutpatients intravenous antimicrobial therapy (opat)

Identifiers

PMID34900504
PMCPMC8649972
OpenAlexW4200364350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.