Evidence map›Paper›PMID 34900440›Full record

ArticlePeerJ2021

Risk factors associated with prolonged viral clearance in patients with a refractory course of COVID-19: a retrospective study.

Weitao Zhuang, Shujie Huang, Dongya Wang, Lulu Zha, Wei Xu, Guibin Qiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weitao Zhuang *Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China.
Shujie Huang *Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China.
Dongya WangDepartment of Hyperbaric Oxygen and Rehabilitation, General Hospital of Southern Theater Command, Chinese People's Liberation Army, Guangzhou, Guangdong, China.
Lulu ZhaThe Fifth Department of Infectious Diseases, Huoshenshan Hospital, Wuhan, China.
Wei XuSchool of Public Health and Management, Chongqing Medical University, Chongqing, China.
Guibin QiaoDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to characterize a cohort of patients with a refractory course of COVID-19, and to investigate factors associated with the duration of viral clearance (DoVC). MATERIALS &

methodsA total of 65 patients with refractory COVID-19 were retrospectively enrolled from Huoshenshan Hospital. Univariate analysis and multivariate analysis were performed to examine the potential association between clinicopathologic characteristics and the DoVC.

resultsThe median DoVC in the overall study cohort was 48 days (ranged from 21 to 104 days). Multivariate analysis indicated that fever at illness onset (Hazard ratio (HR) = 4.897, 95% CI [1.809-13.260],

conclusionThe current study suggested that clinical characteristics such as fever at illness onset, a high serum level of AST or SARS-CoV-2 IgG were associated with delayed viral clearance. Patients with these characteristics might need a more individualized treatment strategy to accelerate their recovery from the refractory COVID-19.

Indexed as

COVID-19RefractoryReinfectionRisk factorsViral clearance

Identifiers

PMID34900440
PMCPMC8621710

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