Evidence map›Paper›PMID 34900383›Full record

ReviewMycology2021

Adhesins in the virulence of opportunistic fungal pathogens of human.

Amrita Kumari, Ankita H Tripathi, Poonam Gautam, Rekha Gahtori, Amit Pande, Yogendra Singh, Taruna Madan, Santosh K Upadhyay

Open access · goldAbstract readReview
In one paragraph

Review in Mycology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Frontiers in microbiology · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Infection and drug resistance · 2025
    Article
  13. Review
  14. Mycology · 2024
    Article
  15. Article
  16. Article
  17. Fibronectin-binding molecules of Scedosporium apiospermum: focus on adhesive events.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  18. Typing ofPathogens (Basel, Switzerland) · 2023
    Article
  19. Construction ofVaccines · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Amrita KumariDepartment of Biotechnology, Sir J.C. Bose Technical campus, Kumaun University, Nainital, India.
Ankita H TripathiDepartment of Biotechnology, Sir J.C. Bose Technical campus, Kumaun University, Nainital, India.
Poonam GautamICMR-National Institute of Pathology, New Delhi, India.
Rekha GahtoriDepartment of Biotechnology, Sir J.C. Bose Technical campus, Kumaun University, Nainital, India.
Amit PandeDirectorate of Coldwater Fisheries Research (DCFR), Nainital, India.
Yogendra SinghDepartment of Zoology, University of Delhi, New Delhi, India.
Taruna MadanICMR-National Institute for Research in Reproductive Health (NIRRH), Mumbai, India.
Santosh K UpadhyayDepartment of Biotechnology, Sir J.C. Bose Technical campus, Kumaun University, Nainital, India.
Kumaun University · INDirectorate of Coldwater Fisheries Research · INNational Institute for Research in Reproductive Health · INNational Institute of Pathology · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-related disease and death among immune-compromised patients. Adhesins are cell-surface exposed proteins or glycoproteins of pathogens that bind to the extracellular matrix (ECM) constituents or mucosal epithelial surfaces of the host cells. The forces of interaction between fungal adhesins and host tissues are accompanied by ligand binding, hydrophobic interactions and protein-protein aggregation. Adherence is the primary and critical step involved in the pathogenesis; however, there is limited information on fungal adhesins compared to that on the bacterial adhesins. Except a few studies based on screening of proteome for adhesin identification, majority are based on characterization of individual adhesins. Recently, based on their characteristic signatures, many putative novel fungal adhesins have been predicted using bioinformatics algorithms. Some of these novel adhesin candidates have been validated by

Indexed as

adherence phenomenonAdhesinadhesionGPI-anchored proteinshost–pathogen interactioninfectious propagulesmorphotypes

Identifiers

PMID34900383
PMCPMC8654403
OpenAlexW3212692410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.