Evidence map›Paper›PMID 34900353›Full record

ArticleInternational journal of hepatology2021

Diastolic Dysfunction Is a Predictor of Poor Survival in Patients with Decompensated Cirrhosis.

Manas Kumar Behera, Surendra Nath Swain, Manoj Kumar Sahu, Gaurav Kumar Behera, Debakanta Mishra, Jimmy Narayan, Ayaskant Singh, Shobhit Agarwal, Pradeep Kumar Mallick

Open access · goldAbstract read
In one paragraph

Article in International journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. The Cardiohepatic Axis in Cirrhosis.JACC. Basic to translational science · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Manas Kumar BeheraDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.
Surendra Nath SwainDepartment of Medicine, IMS and SUM Hospital, Bhubaneswar, India.
Manoj Kumar SahuDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.
Gaurav Kumar BeheraDepartment of Cardiology, IMS and SUM Hospital, Bhubaneswar, India.
Debakanta MishraDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.
Jimmy NarayanDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.ORCID https://orcid.org/0000-0002-8451-1558
Ayaskant SinghDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.
Shobhit AgarwalDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.ORCID https://orcid.org/0000-0001-9777-291X
Pradeep Kumar MallickDepartment of Gastroenterology, IMS and SUM Hospital, Bhubaneswar, India.
Institute of Medical Sciences and Sum Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular diastolic dysfunction (LVDD) appears to be the earliest cardiac disturbance in cirrhosis patients. There are many previous reports reporting the significance of severity of LVDD on the outcome of liver transplantation or TIPS insertion, a few Indian studies have addressed the role of LVDD on survival in decompensated cirrhosis. The objective of this study is to assess the effect of LVDD on the survival of decompensated cirrhotic patients.

methodsWe prospectively evaluated 92 decompensated cirrhotic patients from April 2015 to March 2017 at IMS and SUM Hospital, Bhubaneswar, India. 2D echocardiography with tissue Doppler imaging was used to evaluate cardiac function, as per the American society of echocardiography guidelines. The primary endpoint was to evaluate the effect of LVDD on overall mortality.

resultsNinety-two decompensated cirrhotic patients were evaluated in this prospective cohort study. Twenty-eight out of 92 patients (30%) died due to liver-related complications after a follow-up of 24 months. The decompensated cirrhotic patients with MELD score ≥ 15 had a significantly higher

conclusion: The presence of LVDD and low serum albumin were independent predictors of mortality in decompensated cirrhotic patients. Hence, LVDD is an indicator of advanced cirrhosis and mortality.

Identifiers

PMID34900353
PMCPMC8660240
OpenAlexW3217766133

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.