Evidence map›Paper›PMID 34900144›Full record

ArticleAvicenna journal of medical biotechnology

A Cross-Sectional Study for Evaluation of KRAS and BRAF Mutations by Reverse Dot Blot, PCR-RFLP, and Allele-Specific PCR Methods Among Patients with Colorectal Cancer.

Fatemeh Sheikhsofla, Behzad Poopak, Sajjad Firuzyar, Fatemeh Roudbari, Mojtaba Ghadiany

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fatemeh SheikhsoflaDepartment of Cellular and Molecular Biology, University of Mazandaran, Mazandaran, Iran.
Behzad PoopakDepartment of Clinical Laboratory Sciences, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran.
Sajjad FiruzyarRazi Vaccine and Serum Research Institute of Karaj, Karaj, Iran.
Fatemeh RoudbariDepartment of Virology, University of Mazandaran, Mazandaran, Iran.
Mojtaba GhadianyDepartment of Hematology and Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IRUniversity of Mazandaran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThis study was performed on 50 Formalin-Fixed Paraffin-Embedded (FFPE) tissue blocks of patients diagnosed with colorectal cancer. After DNA extraction,

results

conclusionThese findings suggest that PCR-RFLP and allele-specific PCR methods are suitable for screening the presence of the mutations in

Indexed as

Allele-Specific PCRBRAFColorectal neoplasmsKRASPCR-RFLPReverse dot blot

Identifiers

PMID34900144
PMCPMC8606106
OpenAlexW4226390589

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.