ArticleRevista brasileira de ortopedia2021
Ankle Osteoarthritis.
Article in Revista brasileira de ortopedia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Isolated Displaced Chaput Fracture (Rammelt Type III) With Significant Intra-articular Displacement: A Case Report.Cureus · 2026Article
- Retrospective analysis of platelet rich plasma injections for ankle osteoarthritis in athletic population.BMC musculoskeletal disorders · 2026Article
- Plate versus screw fixation and long-term ankle osteoarthritis in posterior malleolar fractures: A Bartoníček-based cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Imaging Anatomy of the Ankle in Normal and Pathological States: A Clinically Focused Pictorial Review.Cureus · 2025Review
- Intra-articular treatments for hindfoot osteoarthritis.World journal of orthopedics · 2025Article
- Standardized Morphological Modeling and Simulation-Based Validation of a Novel Tibiotalar Fusion Implant.Bioengineering (Basel, Switzerland) · 2025Article
- PATHOPHYSIOLOGY OF POSTTRAUMATIC ANKLE OSTEOARTHRITIS: A MULTICENTER PERSPECTIVE.Acta ortopedica brasileira · 2024Article
- Hybrid-Total Ankle Arthroplasty (H-TAA) for Failed Talar Component in Mobile-Bearing Total Ankle Arthroplasty.Journal of clinical medicine · 2023Article
- The use of platelet-rich plasma in management of musculoskeletal pain: a narrative review.Journal of Yeungnam medical science · 2022Article
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is characterized by a chronic, progressive and irreversible degradation of the joint surface associated with joint inflammation. The main etiology of ankle OA is post-traumatic and its prevalence is higher among young and obese people. Despite advances in the treatment of fractures around the ankle, the overall risk of developing post-traumatic ankle OA after 20 years is almost 40%, especially in Weber type B and C bimalleolar fractures and in fractures involving the posterior tibial border. In talus fractures, this prevalence approaches 100%, depending on the severity of the lesion and the time of follow-up. In this context, the current understanding of the molecular signaling pathways involved in senescence and chondrocyte apoptosis is fundamental. The treatment of ankle OA is staged and guided by the classification systems and local and patient conditions. The main problems are the limited ability to regenerate articular cartilage, low blood supply, and a shortage of progenitor stem cells. The present update summarizes recent scientific evidence of post-traumatic ankle OA with a major focus on changes of the synovia, cartilage and synovial fluid; as well as the epidemiology, pathophysiology, clinical implications, treatment options and potential targets for therapeutic agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.