Evidence map›Paper›PMID 34900036›Full record

ArticleArchives of medical science : AMS2021

Effect of gestational weight gain on insulin resistance mediated by serum adipokine concentrations in advanced maternal age.

Beibei Dong, Jinfang Sun, Mengmeng Zhi, Manman Han, Hao Lin, Hong Yu, Ling Li

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Beibei DongDepartment of Endocrinology, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China.
Jinfang SunKey Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, China.
Mengmeng ZhiDepartment of Endocrinology, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China.
Manman HanDepartment of Endocrinology, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China.
Hao LinPancreatic Research Institute, Southeast University, Nanjing, China.
Hong YuDepartment of Obstetrics and Gynecology, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China.
Ling LiDepartment of Endocrinology, ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China.
Southeast University · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWith the implementation of the universal two-child policy, the number of pregnant women of advanced maternal age (AMA) will increase steadily. We aimed to investigate whether the effect of gestational weight gain on insulin resistance (IR) before delivery was mediated by serum adipokine concentrations in AMA. MATERIAL AND

methodsThis cross-sectional study included 80 pregnant women of AMA recruited consecutively before delivery from the Department of Obstetrics and Gynecology between August 2016 and July 2017. At delivery, maternal weight during the third trimester was recorded and serum adipokines were measured. IR was calculated using the homeostasis model assessment 2 (HOMA2) method.

resultsWeight gain (WG) during the third trimester was positively associated with serum leptin concentrations (

conclusionsTaken together, our findings suggest that the relationship between WG during the third trimester and IR was mediated by serum leptin concentrations in AMA, but not serum adiponectin concentrations.

Indexed as

adiponectinadvanced maternal agegestational weight gaininsulin resistanceleptin

Identifiers

PMID34900036
PMCPMC8641507
OpenAlexW2946032423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.