Evidence map›Paper›PMID 34900027›Full record

SynthesisDisease markers2021

Prognostic Value of lncRNA PVT1 for Patients with Gastric Cancer: A Meta-Analysis.

Jinyong Hao, Bo Yuan, Yani Gou, Jichun Ma, Xiaojun Huang

Open access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Review
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jinyong HaoDepartment of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, China.ORCID https://orcid.org/0000-0001-8277-8294
Bo YuanDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Yani GouDepartment of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, China.
Jichun MaFirst Clinical Medical College, Lanzhou University, Lanzhou, China.
Xiaojun HuangDepartment of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, China.ORCID https://orcid.org/0000-0002-1196-9381
Lanzhou University Second Hospital · CNFirst Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the prognostic value of lncRNA PVT1 for patients with gastric cancer.

methodsA comprehensive literature searching was performed in PubMed, Cochrane Library, Web of Science, Embase, CNKI, CBM, and Wanfang Database to identify published studies on the expression level of lncRNA PVT1 in human gastric cancer. STATA 12.0 was conducted to perform the meta-analysis. Clinical outcomes including patients' age, genders, TNM stage, OS, and DFS were assessed in the study.

resultsA total of 8 studies involving 747 patients were included in this meta-analysis. The results of meta-analysis showed that higher expression level of lncRNA PVT1 was associated with GC patients' gender (for male: OR = 2.27, 95% CI: 1.67~3.07,

conclusionHigher expression level of lncRNA PVT1 is significantly associated with GC patients' gender, invasion depth, poorer OS, and worse DFS. lncRNA PVT1 might act as a novel predictive biomarker of poor prognosis and clinicopathological characteristics for gastric cancer.

Indexed as

Biomarkers, TumorHumansPrognosisRNA, Long NoncodingStomach NeoplasmsBiomarkers, TumorPVT1 long-non-coding RNA, humanRNA, Long Noncoding

Identifiers

PMID34900027
PMCPMC8660201
OpenAlexW3216509266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.