Evidence map›Paper›PMID 34900025›Full record

ArticleDisease markers2021

Regulatory Mechanism of LINC00152 on Aggravating Heart Failure through Triggering Fibrosis in an Infarcted Myocardium.

Lizhong Song, Xiujuan Duan, Xiaojuan Zeng, Xinglian Duan, Li Li

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lizhong SongDepartment of Emergency, Shanxi Cardiovascular Disease Hospital, Taiyuan, Shanxi Province, China.
Xiujuan DuanDepartment of Cardiology, The Eighth People's Hospital of Hengshui City, Hengshui, China.
Xiaojuan ZengDepartment of Cardiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xinglian DuanDepartment of Cardiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li LiDepartment of Cardiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0003-2453-558X
Chongqing Medical University · CNHengshui University · CNShanxi Cardiovascular Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo elucidate the role of LINC00152 in the progression of heart failure following myocardial infarction.

resultsSerum level of LINC00152 was elevated in AMI patients. ROC curves demonstrated the diagnostic potential of LINC00152 in AMI (95% CI: 0.806-0.940,

conclusionsBy downregulating Smad7, LINC00152 aggravates heart failure following AMI

Indexed as

AnimalsDisease Models, AnimalDisease ProgressionFibrosisHeart FailureHeart Function TestsHumansMaleMiceMice, Inbred C57BLMyocardial InfarctionMyofibroblastsRNA, Long Noncodinglong non-coding RNA Linc00152, humanRNA, Long Noncoding

Identifiers

PMID34900025
PMCPMC8654522
OpenAlexW3216131395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.