Evidence map›Paper›PMID 34899860›Full record

ArticleFrontiers in genetics2021

Characterization of Loss-Of-Function

Pauline Le Tanno, Mathilde Folacci, Jean Revilloud, Laurence Faivre, Gabriel Laurent, Lucile Pinson, Pascal Amedro, Gilles Millat, Alexandre Janin, Michel Vivaudou and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The network of cardiac KNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  4. Chronic Propafenone Application Increases Functional KPharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Pauline Le TannoUniversité Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, Grenoble, France.
Mathilde FolacciCEA, CNRS, Institut de Biologie Structurale, Université Grenoble Alpes, Grenoble, France.
Jean RevilloudCEA, CNRS, Institut de Biologie Structurale, Université Grenoble Alpes, Grenoble, France.
Laurence FaivreMedical Genetics Department, Dijon Bourgogne University Hospital, François Mitterand Hospital, Dijon, France.
Gabriel LaurentCardiology Department, Dijon Bourgogne University Hospital, François Mitterand Hospital, Dijon, France.
Lucile PinsonMedical Genetics Department, University Hospital, Montpellier, France.
Pascal AmedroPediatric and Congenital Cardiology Department, Clinical Investigation Centre, PhyMedExp, CNRS, INSERM, University of Montpellier, University Hospital, Montpellier, France.
Gilles MillatLaboratoire de Cardiogénétique Moléculaire, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Lyon, France.
Alexandre JaninLaboratoire de Cardiogénétique Moléculaire, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Lyon, France.
Michel VivaudouCEA, CNRS, Institut de Biologie Structurale, Université Grenoble Alpes, Grenoble, France.
Nathalie Roux-BuissonUniversité Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, Grenoble, France.
Julien FauréUniversité Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, Grenoble, France.
Centre Hospitalier Universitaire de Montpellier · FRHospices Civils de Lyon · FRMaison des Sciences sociales et des Humanités de Dijon · FRCentre Hospitalier Universitaire de Grenoble · FRCentre National de la Recherche Scientifique · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInserm · FRInstitut de Biologie Structurale · FRUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Andersen-Tawil Syndrome (ATS) is a rare disease defined by the association of cardiac arrhythmias, periodic paralysis and dysmorphic features, and is caused by

Indexed as

Andersen-Tawil syndromecatecholaminergic polymorphic ventricular tachycardiafunctionnal characterizationKCNJ2 variantsKir2.1 channelPierre Robin sequence

Identifiers

PMID34899860
PMCPMC8655864
OpenAlexW3216436359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.