Evidence map›Paper›PMID 34899823›Full record

ReviewFrontiers in genetics2021

Association Between

Hao Meng, Shaoyan Huang, Yali Yang, Xiaofeng He, Liping Fei, Yuping Xing

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Effect of vitamin BBMJ open · 2024
    Pooled it
  2. Article
  3. Article
  4. Frontiers in pharmacology · 2026
    Article
  5. Common Methylenetetrahydrofolate Reductase PolymorphismDiagnostics (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Susceptibility to hypertension based onFrontiers in cardiovascular medicine · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Association of the methylenetetrahydrofolate reductase (The Journal of international medical research · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. The association ofFrontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hao MengDepartment of Cardiovascular Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Shaoyan HuangDepartment of Endocrinology, Shaogauan First People's Hospital, Shaoguan, China.
Yali YangDepartment of Cardiovascular Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Xiaofeng HeDepartment of science and education, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Liping FeiDepartment of Cardiovascular Medicine, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Yuping XingNeurology Department, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Changzhi Medical College · CNShaoguan Railway Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the 1990s, there have been a lot of research on single-nucleotide polymorphism (SNP) and different diseases, including many studies on 5,10-methylenetetrahydrofolate reductase (

objectivesThis study aims to explore the degree of risk correlation between two

methodsPubMed, EMBASE, the Cochrane Library, CNKI, and Wan Fang electronic databases were searched to identify relevant studies. We evaluated the relation between the

resultsOverall, harboring the variant of

conclusionThe positive relationships between

Indexed as

BFDPEssential hypertensionFPRPMTHFRRs1801131Rs1801133Venice criteria

Identifiers

PMID34899823
PMCPMC8662810
OpenAlexW3216183769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.