Evidence map›Paper›PMID 34899753›Full record

SynthesisFrontiers in immunology2021

Intercepting Premalignant, Preinvasive Breast Lesions Through Vaccination.

Nadia Nocera Zachariah, Amrita Basu, Namrata Gautam, Ganesan Ramamoorthi, Krithika N Kodumudi, Nagi B Kumar, Loretta Loftus, Brian J Czerniecki

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Breast cancer prevention by prophylactic Lalba mRNA-LNP vaccination.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nadia Nocera ZachariahDepartment of Breast Surgery, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Amrita BasuClinical Science Division, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Namrata GautamClinical Science Division, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Ganesan RamamoorthiClinical Science Division, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Krithika N KodumudiClinical Science Division, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Nagi B KumarClinical Science Division, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Loretta LoftusDepartment of Breast Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Brian J CzernieckiDepartment of Breast Surgery, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Moffitt Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) prevention remains the ultimate cost-effective method to reduce the global burden of invasive breast cancer (IBC). To date, surgery and chemoprevention remain the main risk-reducing modalities for those with hereditary cancer syndromes, as well as high-risk non-hereditary breast lesions such as ADH, ALH, or LCIS. Ductal carcinoma

Indexed as

VaccinationAnimalsAntigens, NeoplasmBreast Carcinoma In SituBreast NeoplasmsCancer VaccinesCarcinoma, Intraductal, NoninfiltratingDisease ProgressionFemaleHumansNeoplasm InvasivenessPrecancerous ConditionsTumor MicroenvironmentAntigens, NeoplasmCancer VaccinesADHbreast cancerDCISdendritic cellimmunosurveillanceLCIStumor-associated antigenvaccine

Identifiers

PMID34899753
PMCPMC8652247
OpenAlexW3215891161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.