Evidence map›Paper›PMID 34899686›Full record

ArticleFrontiers in immunology2021

The Role of Vasoactive Intestinal Peptide and Mast Cells in the Regulatory Effect of

Xiaofan Song, Shanyao Pi, Yueming Gao, Fengxia Zhou, Shuqi Yan, Yue Chen, Lei Qiao, Xina Dou, Dongyan Shao, Chunlan Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Microbiology spectrum · 2026
    Article
  2. Review
  3. Article
  4. The interplay between probiotics and mast cells in gut inflammation: a mini-review.Frontiers in cellular and infection microbiology · 2026
    Review
  5. DietaryFrontiers in microbiomes · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Contribution ofLife (Basel, Switzerland) · 2022
    Review
  11. Crosstalk between gut microbiota and renal ischemia/reperfusion injury.Frontiers in cellular and infection microbiology · 2022
    Review
  12. Selenium Nanoparticles-EnrichedInternational journal of nanomedicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaofan SongThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Shanyao PiThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Yueming GaoThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Fengxia ZhouThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Shuqi YanThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Yue ChenThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Lei QiaoThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Xina DouThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Dongyan ShaoThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Chunlan XuThe Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Northwestern Polytechnical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasoactive intestinal peptide (VIP) plays an important role in the neuro-endocrine-immune system. Mast cells (MCs) are important immune effector cells. This study was conducted to investigate the protective effect of

Indexed as

Lacticaseibacillus caseiAnimalsCoculture TechniquesEnterotoxigenic Escherichia coliGastrointestinal MicrobiomeIntestinal MucosaMast CellsMiceMice, Inbred C57BLSwineVasoactive Intestinal PeptideVasoactive Intestinal Peptideintestinal barrierLactobacillus casei ATCC 393mast cellsmucosal immuneprobioticvasoactive intestinal peptide

Identifiers

PMID34899686
PMCPMC8657605
OpenAlexW3215532658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.