Evidence map›Paper›PMID 34899235›Full record

ArticleCase reports in oncology

Conversion from Positive to Negative EGFR Mutation due to Clonal Selection during Long-Term Treatment with Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors: A Case Report.

Masatomo Ueda, Masashi Namba, Kentaro Tokumo, Tadashi Senoo, Wataru Okamoto, Masami Yamauchi, Noboru Hattori, Kazuhiko Sugiyama

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Masatomo UedaPostgraduate Clinical Training Center, Hiroshima University Hospital, Hiroshima, Japan.
Masashi NambaDepartment of Clinical Oncology, Hiroshima University Hospital, Hiroshima, Japan.
Kentaro TokumoDepartment of Clinical Oncology, Hiroshima University Hospital, Hiroshima, Japan.
Tadashi SenooDepartment of Respiratory Medicine, National Hospital Organization, Kure Medical Center, Hiroshima, Japan.
Wataru OkamotoCancer Treatment Center, Hiroshima University Hospital, Hiroshima, Japan.
Masami YamauchiDepartment of Clinical Oncology, Hiroshima University Hospital, Hiroshima, Japan.
Noboru HattoriDepartment of Respiratory Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Kazuhiko SugiyamaDepartment of Clinical Oncology, Hiroshima University Hospital, Hiroshima, Japan.
Hiroshima University Hospital · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 77-year-old woman with postoperative recurrent non-small cell lung adenocarcinoma, which exhibited an

Indexed as

Epidermal growth factor receptor mutationErlotinibGefitinibMechanisms of resistanceNon-small cell lung cancer

Identifiers

PMID34899235
PMCPMC8613632
OpenAlexW4200507602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.