Evidence map›Paper›PMID 34899182›Full record

ArticleFrontiers in molecular neuroscience2021

Anne-Kathrin Lutz, Andrea Pérez Arévalo, Valentin Ioannidis, Nadine Stirmlinger, Maria Demestre, Richard Delorme, Thomas Bourgeron, Tobias M Boeckers

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Epigenetic Consequences of In Utero PFAS Exposure: Implications for Development and Long-Term Health.International journal of environmental research and public health · 2025
    Review
  8. Autism patient-derived SHANK2BMolecular psychiatry · 2024
    Article
  9. Rodent Models for ASD Biomarker Development.Advances in neurobiology · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Gene×environment interactions in autism spectrum disorders.Current topics in developmental biology · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Anne-Kathrin LutzInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Andrea Pérez ArévaloInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Valentin IoannidisInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Nadine StirmlingerInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Maria DemestreInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Richard DelormeHôpital Robert-Debré, Paris, France.
Thomas BourgeronGénétique Humaine et Fonctions Cognitives, Institut Pasteur, Université Paris Diderot, Paris, France.
Tobias M BoeckersInstitute for Anatomy and Cell Biology, Ulm University, Ulm, Germany.
Universität Ulm · DEGerman Center for Neurodegenerative Diseases · DEHôpital Robert-Debré · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SHANK2 (ProSAP1) is a postsynaptic scaffolding protein of excitatory synapses in the central nervous system and implicated in the development of autism spectrum disorders (ASD). Patients with mutations in

Indexed as

ASDERK1/2hiPSCsneurodevelopmentSHANK2

Identifiers

PMID34899182
PMCPMC8662699
OpenAlexW3216919013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.