Evidence map›Paper›PMID 34898422›Full record

ArticleMicrobial genomics2021

Unique roles of vaginal

Abigail L Glascock, Nicole R Jimenez, Sam Boundy, Vishal N Koparde, J Paul Brooks, David J Edwards, Jerome F Strauss Iii, Kimberly K Jefferson, Myrna G Serrano, Gregory A Buck and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Abigail L GlascockLife Sciences, Virginia Commonwealth University, Richmond, VA, USA.
Nicole R JimenezDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Sam BoundyDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Vishal N KopardeLife Sciences, Virginia Commonwealth University, Richmond, VA, USA.
J Paul BrooksCenter for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, VA, USA.
David J EdwardsCenter for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, VA, USA.
Jerome F Strauss IiiCenter for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, VA, USA.
Kimberly K JeffersonDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Myrna G SerranoDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Gregory A BuckDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Jennifer M FettweisDepartment of Microbiology & Immunology, Virginia Commonwealth University, Richmond, VA, USA.
Virginia Commonwealth University · US

Funding

A Multi-'omic Analysis of the Vaginal Microbiome during PregnancyU54HD080784 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI BUCK, GREGORY ALLEN, JEFFERSON, KIMBERLY KAY · 2014 to 2015
$8.2M
The Vaginal Microbiome: Disease, Genetics and the EnvironmentUH3AI083263 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI BUCK, GREGORY ALLEN · 2010 to 2012
$6.8M
Virginia Commonwealth University Initiative for Maximizing Student DevelopmentR25GM090084 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI AKBARALI, HAMID I, LLOYD, JOYCE A. · 2010 to 2022
$5.2M
Virginia Commonwealth University Postbaccalaureate Research Education ProgramR25GM089614 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI Rebecca Kelley Martin · 2010 to 2026
$4.9M
The Influence of HPV on Preterm Birth via Immunomodulation of the MicrobiomeR01HD092415 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI BUCK, GREGORY ALLEN · 2017 to 2021
$3.6M
Transmission of Maternal Vaginal and Gut Microbiome and Obesity Risk in OffspringR21HD092965 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI FETTWEIS, JENNIFER MAUREEN, WICKHAM, EDMOND PRYCE · 2017 to 2018
$416k
NIAID NIH HHS UH3 AI083263NICHD NIH HHS R01 HD092415NICHD NIH HHS R21 HD092965NICHD NIH HHS U54 HD080784NIGMS NIH HHS R25 GM089614NIGMS NIH HHS R25 GM090084
6 · The paper itself

Abstract

The composition of the human vaginal microbiome has been extensively studied and is known to influence reproductive health. However, the functional roles of individual taxa and their contributions to negative health outcomes have yet to be well characterized. Here, we examine two vaginal bacterial taxa grouped within the genus

Indexed as

Bacterial ProteinsBase CompositionCase-Control StudiesEvolution, MolecularFemaleGene Expression Regulation, BacterialGenome, BacterialGenome SizeHigh-Throughput Nucleotide SequencingHumansMegasphaeraPhylogenyPregnancyReproductive HealthRNA, Ribosomal, 16SSequence Analysis, DNABacterial ProteinsRNA, Ribosomal, 16SBVMegasphaeratrichomoniasisvaginal microbiome

Identifiers

PMID34898422
PMCPMC8767330
OpenAlexW4226099551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.